-
1
APP deficiency did not affect the mRNA level of <i>Scn8a</i> in cerebellar PCs.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
2
Source data and statistical details for figures.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
3
L7 promoter-driven Cre recombinase expression is restricted to PCs in the cerebellar cortex.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
4
Nav1.6 mediated the deficits of PC firing and motor function in APP-null mice.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
5
-
6
Exogenous APP expression restored the Nav1.6 currents and ameliorated the abnormalities in the firing patterns of PCs of APP-null mice.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
7
Antibody validation for Nav1.6 and Nav1.1-EGFP in transfected HEK293 cells.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
8
-
9
APP deficiency does not alter PC development or induce degeneration.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
10
APP deficiency selectively reduces Nav1.6-mediated Na<sup>+</sup> currents in cerebellar PCs.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
11
Nav1.6 Mediates most of the persistent and resurgent sodium currents in cerebellar PCs.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
12
APP-null mice exhibit motor function deficits.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
13
Exogenous amyloid precursor protein (APP) expression restored the defects of the sIPSCs evoked by Nav1.6-mediated Purkenji cell inputs in APP-null mice.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
14
Cerebellar Purkinje cell (PC)-specific amyloid precursor protein (APP) expression modulates motor function.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
15
PoTX potentiates persistent sodium currents in APP-null PCs.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
16
Validation of Nav1.6 and Nav1.1 contributions to sodium currents in PCs.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
17
Full-length APP is required for the rescue of motor deficit in APP-null mice.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”
-
18
APP deficiency impairs the normal firing patterns of PCs.
Publicat 2025Altres autors: “…Tong-Xuan Wu (22676555)…”