YhbO Protects Cells against Multiple Stresses

YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Abdallah, Jad (author)
مؤلفون آخرون: Caldas, Teresa (author), Kthiri, Fatoum (author), Kern, Renee (author), Richarme, Gilbert (author)
التنسيق: article
منشور في: 2007
الوصول للمادة أونلاين:http://hdl.handle.net/10725/4163
http://dx.doi.org/10.1128/JB.01208-07
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://jb.asm.org/content/189/24/9140.short
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الوصف
الملخص:YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management.