Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells
Cdc42 plays a central role in regulating the actin cytoskeleton and maintaining cell polarity. Here, we show that Cdc42 is crucial for epidermal growth factor (EGF)- stimulated protrusion in MTLn3 carcinoma cells. When stimulated with EGF, carcinoma cells showed a rapid increase in activated Cdc42 t...
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| Main Author: | El-Sibai, Mirvat (author) |
|---|---|
| Other Authors: | Nalbant, Peri (author), Pang, Huan (author), Flinn, Rory J. (author), Sarmiento, Corina (author), Macaluso, Frank (author), Cammer, Michael (author), Condeelis, John S. (author), Hahn, Klaus M. (author), Backer, Jonathan M. (author) |
| Format: | article |
| Published: |
2007
|
| Online Access: | http://hdl.handle.net/10725/2492 http://dx.doi.org/10.1242/jcs.005942 http://jcs.biologists.org/content/120/19/3465 |
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