Supplementation of retrobulbar block with clonidine in vitreoretinal surgery
Study Objective To evaluate the effect of clonidine when added to local anesthetics on duration of postoperative analgesia during retrobulbar block. Design Prospective, randomized controlled trial. Setting Operating room and Postanesthesia Care Unit of a university-affiliated hospital. Subjects 80 A...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , |
| التنسيق: | article |
| منشور في: |
2011
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/3993 http://dx.doi.org/10.1016/j.jclinane.2010.12.014 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.sciencedirect.com/science/article/pii/S0952818011002029 |
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| _version_ | 1864513462783180800 |
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| author | Abi Nader, Elie |
| author2 | Yazbeck-Karam, Vanda G. Siddik-Sayyid, Sahar M. Barakat, Daisy E. Karam, Hoda S. Cherfane, Georges M. Hajj Hussein, Jalal N. |
| author2_role | author author author author author author |
| author_facet | Abi Nader, Elie Yazbeck-Karam, Vanda G. Siddik-Sayyid, Sahar M. Barakat, Daisy E. Karam, Hoda S. Cherfane, Georges M. Hajj Hussein, Jalal N. |
| author_role | author |
| dc.creator.none.fl_str_mv | Abi Nader, Elie Yazbeck-Karam, Vanda G. Siddik-Sayyid, Sahar M. Barakat, Daisy E. Karam, Hoda S. Cherfane, Georges M. Hajj Hussein, Jalal N. |
| dc.date.none.fl_str_mv | 2011 2016-06-09T08:58:21Z 2016-06-09T08:58:21Z 2016-06-09 |
| dc.identifier.none.fl_str_mv | 0952-8180 http://hdl.handle.net/10725/3993 http://dx.doi.org/10.1016/j.jclinane.2010.12.014 Yazbeck-Karam, V. G., Siddik-Sayyid, S. M., Nader, E. L. A., Barakat, D. E., Karam, H. S., Cherfane, G. M., ... & Aouad, M. T. (2011). Supplementation of retrobulbar block with clonidine in vitreoretinal surgery: effect on postoperative pain. Journal of clinical anesthesia, 23(5), 393-397. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.sciencedirect.com/science/article/pii/S0952818011002029 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Journal of Clinical Anesthesia |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery effect on postoperative pain |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Study Objective To evaluate the effect of clonidine when added to local anesthetics on duration of postoperative analgesia during retrobulbar block. Design Prospective, randomized controlled trial. Setting Operating room and Postanesthesia Care Unit of a university-affiliated hospital. Subjects 80 ASA physical status 1, 2, and 3 patients undergoing vitreoretinal surgery with or without scleral buckling. Interventions Patients in the control group (n = 40) received a retrobulbar block with 4.5 mL of lidocaine-bupivacaine and 0.5 mL of saline. Clonidine group patients (n = 40) received 4.5 mL of lidocaine-bupivacaine and 0.5 μg/kg of clonidine in a 0.5 mL volume. Measurements The time to first analgesic request, frequency of postoperative pain, and number of postoperative analgesic requests per patient were assessed. Main Results 37 patients in the control group (92.5%) versus 24 patients (60%) in the clonidine group reported pain postoperatively (P = 0.001), with a shorter time to first analgesic request noted in the control group (4.9 ± 3 vs 11.9 ± 5.3 hrs; P < 0.001). The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001]. Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_0204a3de6a0f4fad17eb2aa5f089a356 |
| identifier_str_mv | 0952-8180 Yazbeck-Karam, V. G., Siddik-Sayyid, S. M., Nader, E. L. A., Barakat, D. E., Karam, H. S., Cherfane, G. M., ... & Aouad, M. T. (2011). Supplementation of retrobulbar block with clonidine in vitreoretinal surgery: effect on postoperative pain. Journal of clinical anesthesia, 23(5), 393-397. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/3993 |
| publishDate | 2011 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Supplementation of retrobulbar block with clonidine in vitreoretinal surgeryeffect on postoperative painAbi Nader, ElieYazbeck-Karam, Vanda G.Siddik-Sayyid, Sahar M.Barakat, Daisy E.Karam, Hoda S.Cherfane, Georges M.Hajj Hussein, Jalal N.Study Objective To evaluate the effect of clonidine when added to local anesthetics on duration of postoperative analgesia during retrobulbar block. Design Prospective, randomized controlled trial. Setting Operating room and Postanesthesia Care Unit of a university-affiliated hospital. Subjects 80 ASA physical status 1, 2, and 3 patients undergoing vitreoretinal surgery with or without scleral buckling. Interventions Patients in the control group (n = 40) received a retrobulbar block with 4.5 mL of lidocaine-bupivacaine and 0.5 mL of saline. Clonidine group patients (n = 40) received 4.5 mL of lidocaine-bupivacaine and 0.5 μg/kg of clonidine in a 0.5 mL volume. Measurements The time to first analgesic request, frequency of postoperative pain, and number of postoperative analgesic requests per patient were assessed. Main Results 37 patients in the control group (92.5%) versus 24 patients (60%) in the clonidine group reported pain postoperatively (P = 0.001), with a shorter time to first analgesic request noted in the control group (4.9 ± 3 vs 11.9 ± 5.3 hrs; P < 0.001). The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001]. Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.PublishedN/A2016-06-09T08:58:21Z2016-06-09T08:58:21Z20112016-06-09Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0952-8180http://hdl.handle.net/10725/3993http://dx.doi.org/10.1016/j.jclinane.2010.12.014Yazbeck-Karam, V. G., Siddik-Sayyid, S. M., Nader, E. L. A., Barakat, D. E., Karam, H. S., Cherfane, G. M., ... & Aouad, M. T. (2011). Supplementation of retrobulbar block with clonidine in vitreoretinal surgery: effect on postoperative pain. Journal of clinical anesthesia, 23(5), 393-397.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://www.sciencedirect.com/science/article/pii/S0952818011002029enJournal of Clinical Anesthesiainfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/39932021-03-19T10:00:50Z |
| spellingShingle | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery Abi Nader, Elie |
| status_str | publishedVersion |
| title | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery |
| title_full | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery |
| title_fullStr | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery |
| title_full_unstemmed | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery |
| title_short | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery |
| title_sort | Supplementation of retrobulbar block with clonidine in vitreoretinal surgery |
| url | http://hdl.handle.net/10725/3993 http://dx.doi.org/10.1016/j.jclinane.2010.12.014 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.sciencedirect.com/science/article/pii/S0952818011002029 |