Notes total mesorectal excision (TME) for patients with rectal neoplasia

Background Natural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopy are emerging, minimally invasive techniques. Total mesorectal excision (TME), the gold standard treatment for patients with resectable distal rectal tumors, is usually performed in an “up-to-down” appr...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Chouillard, E. (author)
مؤلفون آخرون: Khoury, G. (author), Chahine, E. (author), Vincent-Bonnet, B. (author), G|umbs, A. (author), Azoulay, D. (author), Abdalla, Eddie (author)
التنسيق: article
منشور في: 2014
الوصول للمادة أونلاين:http://hdl.handle.net/10725/2636
http://dx.doi.org/10.1007/s00464-014-3573-z
http://link.springer.com/article/10.1007/s00464-014-3573-z
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author Chouillard, E.
author2 Khoury, G.
Chahine, E.
Vincent-Bonnet, B.
G|umbs, A.
Azoulay, D.
Abdalla, Eddie
author2_role author
author
author
author
author
author
author_facet Chouillard, E.
Khoury, G.
Chahine, E.
Vincent-Bonnet, B.
G|umbs, A.
Azoulay, D.
Abdalla, Eddie
author_role author
dc.creator.none.fl_str_mv Chouillard, E.
Khoury, G.
Chahine, E.
Vincent-Bonnet, B.
G|umbs, A.
Azoulay, D.
Abdalla, Eddie
dc.date.none.fl_str_mv 2014
2015-11-20T07:20:44Z
2015-11-20T07:20:44Z
2017-10-12
dc.identifier.none.fl_str_mv 0930-2794
http://hdl.handle.net/10725/2636
http://dx.doi.org/10.1007/s00464-014-3573-z
Chouillard, E., Chahine, E., Khoury, G., Vinson-Bonnet, B., Gumbs, A., Azoulay, D., & Abdalla, E. (2014). NOTES total mesorectal excision (TME) for patients with rectal neoplasia: a preliminary experience. Surgical endoscopy, 28(11), 3150-3157.
http://link.springer.com/article/10.1007/s00464-014-3573-z
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Surgical Endoscopy
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Notes total mesorectal excision (TME) for patients with rectal neoplasia
A preliminary experience
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Background Natural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopy are emerging, minimally invasive techniques. Total mesorectal excision (TME), the gold standard treatment for patients with resectable distal rectal tumors, is usually performed in an “up-to-down” approach, either laparoscopically or via open techniques. A transanal, “down-to-up” TME has already been reported. Our NOTES variant of TME (NOTESTME) is based on a transperineal approach without any form of abdominal assistance. The aim was to reduce further the invasiveness of the procedure while optimizing the anatomical definition of the distal mesorectum. This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. Methods NOTESTME was attempted in 16 patients with distal rectal neoplasia (i.e., distal edge of the tumor lower than the pouch of Douglas, between 0 and 12 cm from the dentate line). Additional inclusion criteria consisted of an ASA status ≤III and the absence of previous abdominal surgery. Results NOTESTME was completed in all patients. Additional abdominal, single-incision laparoscopic assistance was required in 6 (38 %) patients. Mean operative time was 265 min (range 155–440 min). The morbidity rate was 18.8 % (two small bowel obstructions and one pelvic abscess), requiring re-operation in each case. No leaks occurred, and the mortality rate at 30 and 90 days was 0 %. Resection margins were negative in all patients. A median of 17 nodes (range 12–81) was retrieved per specimen. Mean length of hospital stay was 10 days (range 4–29 days). Patients were followed for an average of 7 months (range 3–23 months). Conclusion NOTESTME was feasible and safe in this series of patients with mid- or low rectal tumors. The short-term mortality and morbidity rates are acceptable, with no apparent compromise in the oncological quality of the resection. Larger, randomized controlled trials with long-term follow-up are warranted.
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Chouillard, E., Chahine, E., Khoury, G., Vinson-Bonnet, B., Gumbs, A., Azoulay, D., & Abdalla, E. (2014). NOTES total mesorectal excision (TME) for patients with rectal neoplasia: a preliminary experience. Surgical endoscopy, 28(11), 3150-3157.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
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spelling Notes total mesorectal excision (TME) for patients with rectal neoplasiaA preliminary experienceChouillard, E.Khoury, G.Chahine, E.Vincent-Bonnet, B.G|umbs, A.Azoulay, D.Abdalla, EddieBackground Natural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopy are emerging, minimally invasive techniques. Total mesorectal excision (TME), the gold standard treatment for patients with resectable distal rectal tumors, is usually performed in an “up-to-down” approach, either laparoscopically or via open techniques. A transanal, “down-to-up” TME has already been reported. Our NOTES variant of TME (NOTESTME) is based on a transperineal approach without any form of abdominal assistance. The aim was to reduce further the invasiveness of the procedure while optimizing the anatomical definition of the distal mesorectum. This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. Methods NOTESTME was attempted in 16 patients with distal rectal neoplasia (i.e., distal edge of the tumor lower than the pouch of Douglas, between 0 and 12 cm from the dentate line). Additional inclusion criteria consisted of an ASA status ≤III and the absence of previous abdominal surgery. Results NOTESTME was completed in all patients. Additional abdominal, single-incision laparoscopic assistance was required in 6 (38 %) patients. Mean operative time was 265 min (range 155–440 min). The morbidity rate was 18.8 % (two small bowel obstructions and one pelvic abscess), requiring re-operation in each case. No leaks occurred, and the mortality rate at 30 and 90 days was 0 %. Resection margins were negative in all patients. A median of 17 nodes (range 12–81) was retrieved per specimen. Mean length of hospital stay was 10 days (range 4–29 days). Patients were followed for an average of 7 months (range 3–23 months). Conclusion NOTESTME was feasible and safe in this series of patients with mid- or low rectal tumors. The short-term mortality and morbidity rates are acceptable, with no apparent compromise in the oncological quality of the resection. Larger, randomized controlled trials with long-term follow-up are warranted.PublishedN/A2015-11-20T07:20:44Z2015-11-20T07:20:44Z20142017-10-12Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0930-2794http://hdl.handle.net/10725/2636http://dx.doi.org/10.1007/s00464-014-3573-zChouillard, E., Chahine, E., Khoury, G., Vinson-Bonnet, B., Gumbs, A., Azoulay, D., & Abdalla, E. (2014). NOTES total mesorectal excision (TME) for patients with rectal neoplasia: a preliminary experience. Surgical endoscopy, 28(11), 3150-3157.http://link.springer.com/article/10.1007/s00464-014-3573-zenSurgical Endoscopyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/26362021-03-19T09:59:49Z
spellingShingle Notes total mesorectal excision (TME) for patients with rectal neoplasia
Chouillard, E.
status_str publishedVersion
title Notes total mesorectal excision (TME) for patients with rectal neoplasia
title_full Notes total mesorectal excision (TME) for patients with rectal neoplasia
title_fullStr Notes total mesorectal excision (TME) for patients with rectal neoplasia
title_full_unstemmed Notes total mesorectal excision (TME) for patients with rectal neoplasia
title_short Notes total mesorectal excision (TME) for patients with rectal neoplasia
title_sort Notes total mesorectal excision (TME) for patients with rectal neoplasia
url http://hdl.handle.net/10725/2636
http://dx.doi.org/10.1007/s00464-014-3573-z
http://link.springer.com/article/10.1007/s00464-014-3573-z