Retinal reactive astrocytic tumor
Retinal vasoproliferative tumor is a benign tumor with glial cell and vascular components.1,2 The clinical picture was well characterized by Shields and colleagues.1,3 Histopathologically, the low-grade tumor is composed of glial fibrillary acidic protein–positive spindle cells and vascular channels...
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2014
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| Online Access: | http://hdl.handle.net/10725/10860 http://dx.doi.org/10.1001/jamaophthalmol.2014.299 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://jamanetwork.com/journals/jamaophthalmology/article-abstract/1882156 |
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| _version_ | 1864513467504918528 |
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| author | Shehri, Maha |
| author2 | Bouhenni, Rachida Ghazi, Nicola G. Abu Safieh, Leen Edward, Deepak P. |
| author2_role | author author author author |
| author_facet | Shehri, Maha Bouhenni, Rachida Ghazi, Nicola G. Abu Safieh, Leen Edward, Deepak P. |
| author_role | author |
| dc.creator.none.fl_str_mv | Shehri, Maha Bouhenni, Rachida Ghazi, Nicola G. Abu Safieh, Leen Edward, Deepak P. |
| dc.date.none.fl_str_mv | 2014 2019-06-19T08:24:08Z 2019-06-19T08:24:08Z 2019-06-19 |
| dc.identifier.none.fl_str_mv | 2168-6173 http://hdl.handle.net/10725/10860 http://dx.doi.org/10.1001/jamaophthalmol.2014.299 Shehri, M., Bouhenni, R., Ghazi, N. G., Safieh, L. A., & Edward, D. P. (2014). Retinal reactive astrocytic tumor: gene expression profiling. JAMA ophthalmology, 132(6), 773-775. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://jamanetwork.com/journals/jamaophthalmology/article-abstract/1882156 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | JAMA Ophtalmology |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Retinal reactive astrocytic tumor gene expression profiling |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Retinal vasoproliferative tumor is a benign tumor with glial cell and vascular components.1,2 The clinical picture was well characterized by Shields and colleagues.1,3 Histopathologically, the low-grade tumor is composed of glial fibrillary acidic protein–positive spindle cells and vascular channels.4 A recent study demonstrated that the main component of the lesion was reactive astrocytes and suggested renaming the lesion retinal reactive astrocytic tumor.4 The authors questioned whether Müller cells, the major retinal glia, were involved in the reactive lesions. In this study, we examined the pathologic features and gene expression profile of an excised vasoproliferative tumor and confirmed the expression of 2 important overexpressed and underexpressed genes. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_061de0a1452caadd57d1090aa4df219d |
| identifier_str_mv | 2168-6173 Shehri, M., Bouhenni, R., Ghazi, N. G., Safieh, L. A., & Edward, D. P. (2014). Retinal reactive astrocytic tumor: gene expression profiling. JAMA ophthalmology, 132(6), 773-775. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/10860 |
| publishDate | 2014 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Retinal reactive astrocytic tumorgene expression profilingShehri, MahaBouhenni, RachidaGhazi, Nicola G.Abu Safieh, LeenEdward, Deepak P.Retinal vasoproliferative tumor is a benign tumor with glial cell and vascular components.1,2 The clinical picture was well characterized by Shields and colleagues.1,3 Histopathologically, the low-grade tumor is composed of glial fibrillary acidic protein–positive spindle cells and vascular channels.4 A recent study demonstrated that the main component of the lesion was reactive astrocytes and suggested renaming the lesion retinal reactive astrocytic tumor.4 The authors questioned whether Müller cells, the major retinal glia, were involved in the reactive lesions. In this study, we examined the pathologic features and gene expression profile of an excised vasoproliferative tumor and confirmed the expression of 2 important overexpressed and underexpressed genes.PublishedN/A2019-06-19T08:24:08Z2019-06-19T08:24:08Z20142019-06-19Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2168-6173http://hdl.handle.net/10725/10860http://dx.doi.org/10.1001/jamaophthalmol.2014.299Shehri, M., Bouhenni, R., Ghazi, N. G., Safieh, L. A., & Edward, D. P. (2014). Retinal reactive astrocytic tumor: gene expression profiling. JAMA ophthalmology, 132(6), 773-775.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://jamanetwork.com/journals/jamaophthalmology/article-abstract/1882156enJAMA Ophtalmologyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/108602021-03-19T10:45:17Z |
| spellingShingle | Retinal reactive astrocytic tumor Shehri, Maha |
| status_str | publishedVersion |
| title | Retinal reactive astrocytic tumor |
| title_full | Retinal reactive astrocytic tumor |
| title_fullStr | Retinal reactive astrocytic tumor |
| title_full_unstemmed | Retinal reactive astrocytic tumor |
| title_short | Retinal reactive astrocytic tumor |
| title_sort | Retinal reactive astrocytic tumor |
| url | http://hdl.handle.net/10725/10860 http://dx.doi.org/10.1001/jamaophthalmol.2014.299 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://jamanetwork.com/journals/jamaophthalmology/article-abstract/1882156 |