Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon
HIV genetic variability, phylogenetic relationships, and transmission dynamics were analyzed in 26 HIV-infected patients from Lebanon. Twenty-five specimens were identified as HIV-1 and one as HIV-2 subtype B. The 25 strains were classified into six env-C2-V3 HIV-1 subtypes: B (n = 10), A (n = 11),...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , , , , , , |
| التنسيق: | article |
| منشور في: |
1998
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/5203 http://dx.doi.org/10.3201/eid0404.980418 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640249/pdf/9866744.pdf |
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| _version_ | 1864513465382600704 |
|---|---|
| author | Mokhbat, Jacques E. |
| author2 | Pieniazek, Danuta Baggs, James Matar, Ghassan M. Abdelnoor, Alexander M. Uwaydah, Marwan Bizri, Abdul Rahman Ramos, Artur Janini, Luiz M. Tanuri, Amilcar Fridlund, Carol Heyndrickx, Leo Rayfield, Mark A. Heneine, Walid |
| author2_role | author author author author author author author author author author author author author |
| author_facet | Mokhbat, Jacques E. Pieniazek, Danuta Baggs, James Matar, Ghassan M. Abdelnoor, Alexander M. Uwaydah, Marwan Bizri, Abdul Rahman Ramos, Artur Janini, Luiz M. Tanuri, Amilcar Fridlund, Carol Heyndrickx, Leo Rayfield, Mark A. Heneine, Walid |
| author_role | author |
| dc.creator.none.fl_str_mv | Mokhbat, Jacques E. Pieniazek, Danuta Baggs, James Matar, Ghassan M. Abdelnoor, Alexander M. Uwaydah, Marwan Bizri, Abdul Rahman Ramos, Artur Janini, Luiz M. Tanuri, Amilcar Fridlund, Carol Heyndrickx, Leo Rayfield, Mark A. Heneine, Walid |
| dc.date.none.fl_str_mv | 1998 2017-02-10T08:29:48Z 2017-02-10T08:29:48Z 2017-02-10 |
| dc.identifier.none.fl_str_mv | 1080-6040 http://hdl.handle.net/10725/5203 http://dx.doi.org/10.3201/eid0404.980418 Pieniazek, D., Baggs, J., Hu, D. J., Matar, G. M., Abdelnoor, A. M., Mokhbat, J. E., ... & Tanuri, A. (1998). Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon. Emerging infectious diseases, 4(4), 649. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640249/pdf/9866744.pdf |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Emerging Infections Diseases |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | HIV genetic variability, phylogenetic relationships, and transmission dynamics were analyzed in 26 HIV-infected patients from Lebanon. Twenty-five specimens were identified as HIV-1 and one as HIV-2 subtype B. The 25 strains were classified into six env-C2-V3 HIV-1 subtypes: B (n = 10), A (n = 11), C (n = 1), D (n = 1), G (n = 1), and unclassifiable. Potential recombinants combining parts of viral regions from different subtypes Aenv/Dpol/Agag, Genv/Apol, and the unclassifiable-subtype(env)/unclassifiable-subtype(pol)/Agag were found in three patients. Epidemiologic analysis of travel histories and behavioral risks indicated that HIV-1 and HIV-2 subtypes reflected HIV strains prevalent in countries visited by patients or their sex partners. Spread of complex HIV-subtype distribution patterns to regions where HIV is not endemic may be more common than previously thought. Blood screening for both HIV-1 and HIV-2 in Lebanon is recommended to protect the blood supply. HIV subtype data provide information for vaccine development |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_08e5180c7de76c3b313be55e8286e53c |
| identifier_str_mv | 1080-6040 Pieniazek, D., Baggs, J., Hu, D. J., Matar, G. M., Abdelnoor, A. M., Mokhbat, J. E., ... & Tanuri, A. (1998). Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon. Emerging infectious diseases, 4(4), 649. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/5203 |
| publishDate | 1998 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Introduction of HIV-2 and multiple HIV-1 subtypes to LebanonMokhbat, Jacques E.Pieniazek, DanutaBaggs, JamesMatar, Ghassan M.Abdelnoor, Alexander M.Uwaydah, MarwanBizri, Abdul RahmanRamos, ArturJanini, Luiz M.Tanuri, AmilcarFridlund, CarolHeyndrickx, LeoRayfield, Mark A.Heneine, WalidHIV genetic variability, phylogenetic relationships, and transmission dynamics were analyzed in 26 HIV-infected patients from Lebanon. Twenty-five specimens were identified as HIV-1 and one as HIV-2 subtype B. The 25 strains were classified into six env-C2-V3 HIV-1 subtypes: B (n = 10), A (n = 11), C (n = 1), D (n = 1), G (n = 1), and unclassifiable. Potential recombinants combining parts of viral regions from different subtypes Aenv/Dpol/Agag, Genv/Apol, and the unclassifiable-subtype(env)/unclassifiable-subtype(pol)/Agag were found in three patients. Epidemiologic analysis of travel histories and behavioral risks indicated that HIV-1 and HIV-2 subtypes reflected HIV strains prevalent in countries visited by patients or their sex partners. Spread of complex HIV-subtype distribution patterns to regions where HIV is not endemic may be more common than previously thought. Blood screening for both HIV-1 and HIV-2 in Lebanon is recommended to protect the blood supply. HIV subtype data provide information for vaccine developmentPublishedN/A2017-02-10T08:29:48Z2017-02-10T08:29:48Z19982017-02-10Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1080-6040http://hdl.handle.net/10725/5203http://dx.doi.org/10.3201/eid0404.980418Pieniazek, D., Baggs, J., Hu, D. J., Matar, G. M., Abdelnoor, A. M., Mokhbat, J. E., ... & Tanuri, A. (1998). Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon. Emerging infectious diseases, 4(4), 649.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640249/pdf/9866744.pdfenEmerging Infections Diseasesinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/52032021-03-19T10:00:48Z |
| spellingShingle | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon Mokhbat, Jacques E. |
| status_str | publishedVersion |
| title | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| title_full | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| title_fullStr | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| title_full_unstemmed | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| title_short | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| title_sort | Introduction of HIV-2 and multiple HIV-1 subtypes to Lebanon |
| url | http://hdl.handle.net/10725/5203 http://dx.doi.org/10.3201/eid0404.980418 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640249/pdf/9866744.pdf |