A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV
Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). The consequences of these alterations on the targeting of membrane proteins are poorly understood. Glycosphingolipids are enriched in...
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| Other Authors: | , , , , , |
| Format: | article |
| Published: |
2010
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| Online Access: | http://hdl.handle.net/10725/2347 http://dx.doi.org/10.1007/s10545-010-9114-6 http://link.springer.com/article/10.1007/s10545-010-9114-6 |
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