Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)
Anthrax lethal toxin is a two-component toxin consisting of protective antigen (PrAg), the cell binding and translocation domain, and lethal factor (LF), the catalytic domain, which cleaves all mitogen-activated protein/extracellular regulated kinase kinases (MEKs), leading to the inhibition of the...
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| Format: | masterThesis |
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2020
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| Online Access: | http://hdl.handle.net/10725/13448 https://doi.org/10.26756/th.2022.333 http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php |
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