Current and Emerging Therapies of Severe Epileptic Encephalopathies

In this article, we review the treatment options for the pediatric epileptic encephalopathies and provide an update on the new and emerging therapies targeted at the underlying pathophysiology of many of these syndromes. We illustrate how the identification of the specific genetic and autoimmune cau...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Hani, Abeer J. (author)
مؤلفون آخرون: Mikati, Mohamad A. (author)
التنسيق: article
منشور في: 2016
الوصول للمادة أونلاين:http://hdl.handle.net/10725/4771
http://dx.doi.org/10.1016/j.spen.2016.06.001
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.sciencedirect.com/science/article/pii/S1071909116300079
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الوصف
الملخص:In this article, we review the treatment options for the pediatric epileptic encephalopathies and provide an update on the new and emerging therapies targeted at the underlying pathophysiology of many of these syndromes. We illustrate how the identification of the specific genetic and autoimmune causes has made possible the evaluation and development of novel, better targeted therapies, as and at times, avoidance of potentially offending agents.