Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of infections that are becoming increasingly difficult to combat because of emerging resistance. In this study, 103 S. aureus, 41 MRSA and 62 methicillin-sensitive Staphylococcus aureus isolates, were collected from children in Jord...

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Main Author: Hashwa, Fuad (author)
Other Authors: Tokajian, Sima (author), Shihabi, Asem (author), Khalil, Wassim (author)
Format: article
Published: 2012
Online Access:http://hdl.handle.net/10725/3400
http://dx.doi.org/10.1016/j.diagmicrobio.2012.03.012
http://www.sciencedirect.com/science/article/pii/S0732889312001046
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author Hashwa, Fuad
author2 Tokajian, Sima
Shihabi, Asem
Khalil, Wassim
author2_role author
author
author
author_facet Hashwa, Fuad
Tokajian, Sima
Shihabi, Asem
Khalil, Wassim
author_role author
dc.contributor.none.fl_str_mv
dc.creator.none.fl_str_mv Hashwa, Fuad
Tokajian, Sima
Shihabi, Asem
Khalil, Wassim
dc.date.none.fl_str_mv 2012
2016-03-23T12:17:45Z
2016-03-23T12:17:45Z
2016-03-23
dc.identifier.none.fl_str_mv 0732-8893
http://hdl.handle.net/10725/3400
http://dx.doi.org/10.1016/j.diagmicrobio.2012.03.012
Khalil, W., Hashwa, F., Shihabi, A., & Tokajian, S. (2012). Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan. Diagnostic microbiology and infectious disease, 73(3), 228-230.
http://www.sciencedirect.com/science/article/pii/S0732889312001046
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Diagnostic Microbiology and Infectious Disease
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of infections that are becoming increasingly difficult to combat because of emerging resistance. In this study, 103 S. aureus, 41 MRSA and 62 methicillin-sensitive Staphylococcus aureus isolates, were collected from children in Jordan. Genotyping based on spa and multilocus sequence typing (MLST) revealed 48 different spa types and identified distinct allelic profiles or STs, with the majority belonging to ST80. Pulsed-field gel electrophoresis (PFGE) of 15 different spa types revealed 8 different PFGE types, while SCCmec showed the predominance (53%) of subtype IV. Clustering SCCmec along with MLST revealed that ST80-MRSA-IV was the dominant type. Results obtained suggest that a significant amount of clonal spread is occurring in Jordan. The mechanism of spread of the ST80-IV clone is not known, and control measures are needed to reduce further spread of this or of other clones among children in Jordan.
eu_rights_str_mv openAccess
format article
id LAURepo_180b5e87bfbdf932b8c3809e2cb8dbc0
identifier_str_mv 0732-8893
Khalil, W., Hashwa, F., Shihabi, A., & Tokajian, S. (2012). Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan. Diagnostic microbiology and infectious disease, 73(3), 228-230.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/3400
publishDate 2012
repository.mail.fl_str_mv
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spelling Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from JordanHashwa, FuadTokajian, SimaShihabi, AsemKhalil, WassimMethicillin-resistant Staphylococcus aureus (MRSA) is a major cause of infections that are becoming increasingly difficult to combat because of emerging resistance. In this study, 103 S. aureus, 41 MRSA and 62 methicillin-sensitive Staphylococcus aureus isolates, were collected from children in Jordan. Genotyping based on spa and multilocus sequence typing (MLST) revealed 48 different spa types and identified distinct allelic profiles or STs, with the majority belonging to ST80. Pulsed-field gel electrophoresis (PFGE) of 15 different spa types revealed 8 different PFGE types, while SCCmec showed the predominance (53%) of subtype IV. Clustering SCCmec along with MLST revealed that ST80-MRSA-IV was the dominant type. Results obtained suggest that a significant amount of clonal spread is occurring in Jordan. The mechanism of spread of the ST80-IV clone is not known, and control measures are needed to reduce further spread of this or of other clones among children in Jordan.PublishedN/A2016-03-23T12:17:45Z2016-03-23T12:17:45Z20122016-03-23Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0732-8893http://hdl.handle.net/10725/3400http://dx.doi.org/10.1016/j.diagmicrobio.2012.03.012Khalil, W., Hashwa, F., Shihabi, A., & Tokajian, S. (2012). Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan. Diagnostic microbiology and infectious disease, 73(3), 228-230.http://www.sciencedirect.com/science/article/pii/S0732889312001046enDiagnostic Microbiology and Infectious Diseaseinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/34002018-05-23T05:58:14Z
spellingShingle Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
Hashwa, Fuad
status_str publishedVersion
title Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
title_full Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
title_fullStr Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
title_full_unstemmed Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
title_short Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
title_sort Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan
url http://hdl.handle.net/10725/3400
http://dx.doi.org/10.1016/j.diagmicrobio.2012.03.012
http://www.sciencedirect.com/science/article/pii/S0732889312001046