A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells
urpose Activation of STAT3 has been identified as a central mediator of melanoma growth and metastasis. We hypothesized that WP1066, a novel STAT3 blockade agent, has marked antitumor activity, even against the melanoma metastasis to brain, a site typically refractory to therapies. Experimental Desi...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , , , , , |
| التنسيق: | article |
| منشور في: |
2008
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/6478 http://dx.doi.org/10.1158/1078-0432.CCR-08-0377 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583362/ |
| الوسوم: |
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