Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells

The Rho GTPases Rac and Cdc42 play a central role in the regulation of secretory and cytoskeletal responses in antigen-stimulated mast cells. In this study, we examine the kinetics and mechanism of Rac and Cdc42 activation in the rat basophilic leukemia RBL- 2H3 cells. The activation kinetics of bot...

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Bibliographic Details
Main Author: El-Sibai, Mirvat (author)
Other Authors: Backer, Jonathan M. (author)
Format: article
Published: 2007
Online Access:http://hdl.handle.net/10725/2497
http://dx.doi.org/10.1002/eji.200635875
http://onlinelibrary.wiley.com/doi/10.1002/eji.200635875/full
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