Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound

Background The aim of this study was to determine which EUS characteristics correlate with malignant potential of GISTs. Methods All patients with a diagnosis of GIST based on surgical resection and preoperative EUS at our institution from January 2000 to July 2006 were identified. Pathology reports...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Azar, Riad (author)
مؤلفون آخرون: Shah, Pari (author), Gao, Feng (author), Edmundowicz, Steven A. (author), Early, Dayna S. (author)
التنسيق: article
منشور في: 2009
الوصول للمادة أونلاين:http://hdl.handle.net/10725/4106
http://dx.doi.org/10.1007/s10620-008-0484-7
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://link.springer.com/article/10.1007/s10620-008-0484-7
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author Azar, Riad
author2 Shah, Pari
Gao, Feng
Edmundowicz, Steven A.
Early, Dayna S.
author2_role author
author
author
author
author_facet Azar, Riad
Shah, Pari
Gao, Feng
Edmundowicz, Steven A.
Early, Dayna S.
author_role author
dc.creator.none.fl_str_mv Azar, Riad
Shah, Pari
Gao, Feng
Edmundowicz, Steven A.
Early, Dayna S.
dc.date.none.fl_str_mv 2009
2016-06-20T08:49:26Z
2016-06-20T08:49:26Z
2016-06-20
dc.identifier.none.fl_str_mv 0163-2116
http://hdl.handle.net/10725/4106
http://dx.doi.org/10.1007/s10620-008-0484-7
Shah, P., Gao, F., Edmundowicz, S. A., Azar, R. R., & Early, D. S. (2009). Predicting malignant potential of gastrointestinal stromal tumors using endoscopic ultrasound. Digestive diseases and sciences, 54(6), 1265-1269.
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://link.springer.com/article/10.1007/s10620-008-0484-7
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Digestive Diseases and Sciences
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Background The aim of this study was to determine which EUS characteristics correlate with malignant potential of GISTs. Methods All patients with a diagnosis of GIST based on surgical resection and preoperative EUS at our institution from January 2000 to July 2006 were identified. Pathology reports were used to determine NIH classification of each GIST and EUS exams were reviewed. EUS features were compared to NIH classification of very low/low risk malignant potential or intermediate/high risk malignant potential. Results Fourteen patients had lesions of very low or low risk malignant potential, and 12 patients had lesions of intermediate or high-risk malignant potential. EUS features of tumor size (P = 0.002), irregular extraluminal border (P = 0.005), local invasion (P = 0.02), and heterogeneity (P = 0.02) were statistically significant correlates of intermediate or high risk malignant potential. Conclusions EUS characteristics of tumor size, extraluminal border, depth, and heterogeneity can be used to predict malignant potential of GISTs.
eu_rights_str_mv openAccess
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id LAURepo_1e369ca261437da235ee89ac2bd5afde
identifier_str_mv 0163-2116
Shah, P., Gao, F., Edmundowicz, S. A., Azar, R. R., & Early, D. S. (2009). Predicting malignant potential of gastrointestinal stromal tumors using endoscopic ultrasound. Digestive diseases and sciences, 54(6), 1265-1269.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/4106
publishDate 2009
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spelling Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic UltrasoundAzar, RiadShah, PariGao, FengEdmundowicz, Steven A.Early, Dayna S.Background The aim of this study was to determine which EUS characteristics correlate with malignant potential of GISTs. Methods All patients with a diagnosis of GIST based on surgical resection and preoperative EUS at our institution from January 2000 to July 2006 were identified. Pathology reports were used to determine NIH classification of each GIST and EUS exams were reviewed. EUS features were compared to NIH classification of very low/low risk malignant potential or intermediate/high risk malignant potential. Results Fourteen patients had lesions of very low or low risk malignant potential, and 12 patients had lesions of intermediate or high-risk malignant potential. EUS features of tumor size (P = 0.002), irregular extraluminal border (P = 0.005), local invasion (P = 0.02), and heterogeneity (P = 0.02) were statistically significant correlates of intermediate or high risk malignant potential. Conclusions EUS characteristics of tumor size, extraluminal border, depth, and heterogeneity can be used to predict malignant potential of GISTs.PublishedN/A2016-06-20T08:49:26Z2016-06-20T08:49:26Z20092016-06-20Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0163-2116http://hdl.handle.net/10725/4106http://dx.doi.org/10.1007/s10620-008-0484-7Shah, P., Gao, F., Edmundowicz, S. A., Azar, R. R., & Early, D. S. (2009). Predicting malignant potential of gastrointestinal stromal tumors using endoscopic ultrasound. Digestive diseases and sciences, 54(6), 1265-1269.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://link.springer.com/article/10.1007/s10620-008-0484-7enDigestive Diseases and Sciencesinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/41062021-03-19T10:00:55Z
spellingShingle Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
Azar, Riad
status_str publishedVersion
title Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
title_full Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
title_fullStr Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
title_full_unstemmed Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
title_short Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
title_sort Predicting Malignant Potential of Gastrointestinal Stromal Tumors Using Endoscopic Ultrasound
url http://hdl.handle.net/10725/4106
http://dx.doi.org/10.1007/s10620-008-0484-7
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://link.springer.com/article/10.1007/s10620-008-0484-7