Parenteral nutrition-associated liver complications in children
Parenteral nutrition is a life-saving therapy for patients with intestinal failure. It may be associated with transient elevations of liver enzyme concentrations, which return to normal after parenteral nutrition is discontinued. Prolonged parenteral nutrition is associated with complications affect...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| التنسيق: | article |
| منشور في: |
2002
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/4510 http://dx.doi.org/10.1592/phco.22.3.188.33553 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://onlinelibrary.wiley.com/doi/10.1592/phco.22.3.188.33553/abstract |
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| _version_ | 1864513463705927680 |
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| author | Btaiche, Imad F. |
| author2 | Khalidi, Nabil |
| author2_role | author |
| author_facet | Btaiche, Imad F. Khalidi, Nabil |
| author_role | author |
| dc.creator.none.fl_str_mv | Btaiche, Imad F. Khalidi, Nabil |
| dc.date.none.fl_str_mv | 2002 2016-10-06T07:29:41Z 2016-10-06T07:29:41Z 2016-10-06 |
| dc.identifier.none.fl_str_mv | 0277-0008 http://hdl.handle.net/10725/4510 http://dx.doi.org/10.1592/phco.22.3.188.33553 Btaiche, I. F., & Khalidi, N. (2002). Parenteral Nutrition‐Associated Liver Complications in Children. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 22(2), 188-211. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://onlinelibrary.wiley.com/doi/10.1592/phco.22.3.188.33553/abstract |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Pharmacotherapy |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Parenteral nutrition-associated liver complications in children |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Parenteral nutrition is a life-saving therapy for patients with intestinal failure. It may be associated with transient elevations of liver enzyme concentrations, which return to normal after parenteral nutrition is discontinued. Prolonged parenteral nutrition is associated with complications affecting the hepatobiliary system, such as cholelithiasis, cholestasis, and steatosis. The most common of these is parenteral nutrition-associated cholestasis (PNAC), which may occur in children and may progress to liver failure. The pathophysiology of PNAC is poorly understood, and the etiology is multifactorial. Risk factors include prematurity, long duration of parenteral nutrition, sepsis, lack of bowel motility, and short bowel syndrome. Possible etiologies include excessive caloric administration, parenteral nutrition components, and nutritional deficiencies. Several measures can be undertaken to prevent PNAC, such as avoiding overfeeding, providing a balanced source of energy, weaning parenteral nutrition, starting enteral feeding, and avoiding sepsis. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_1ed1dc96eb2cfcde8ba69e87b52ae57d |
| identifier_str_mv | 0277-0008 Btaiche, I. F., & Khalidi, N. (2002). Parenteral Nutrition‐Associated Liver Complications in Children. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 22(2), 188-211. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/4510 |
| publishDate | 2002 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Parenteral nutrition-associated liver complications in childrenBtaiche, Imad F.Khalidi, NabilParenteral nutrition is a life-saving therapy for patients with intestinal failure. It may be associated with transient elevations of liver enzyme concentrations, which return to normal after parenteral nutrition is discontinued. Prolonged parenteral nutrition is associated with complications affecting the hepatobiliary system, such as cholelithiasis, cholestasis, and steatosis. The most common of these is parenteral nutrition-associated cholestasis (PNAC), which may occur in children and may progress to liver failure. The pathophysiology of PNAC is poorly understood, and the etiology is multifactorial. Risk factors include prematurity, long duration of parenteral nutrition, sepsis, lack of bowel motility, and short bowel syndrome. Possible etiologies include excessive caloric administration, parenteral nutrition components, and nutritional deficiencies. Several measures can be undertaken to prevent PNAC, such as avoiding overfeeding, providing a balanced source of energy, weaning parenteral nutrition, starting enteral feeding, and avoiding sepsis.PublishedN/A2016-10-06T07:29:41Z2016-10-06T07:29:41Z20022016-10-06Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0277-0008http://hdl.handle.net/10725/4510http://dx.doi.org/10.1592/phco.22.3.188.33553Btaiche, I. F., & Khalidi, N. (2002). Parenteral Nutrition‐Associated Liver Complications in Children. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 22(2), 188-211.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://onlinelibrary.wiley.com/doi/10.1592/phco.22.3.188.33553/abstractenPharmacotherapyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/45102021-03-19T10:03:23Z |
| spellingShingle | Parenteral nutrition-associated liver complications in children Btaiche, Imad F. |
| status_str | publishedVersion |
| title | Parenteral nutrition-associated liver complications in children |
| title_full | Parenteral nutrition-associated liver complications in children |
| title_fullStr | Parenteral nutrition-associated liver complications in children |
| title_full_unstemmed | Parenteral nutrition-associated liver complications in children |
| title_short | Parenteral nutrition-associated liver complications in children |
| title_sort | Parenteral nutrition-associated liver complications in children |
| url | http://hdl.handle.net/10725/4510 http://dx.doi.org/10.1592/phco.22.3.188.33553 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://onlinelibrary.wiley.com/doi/10.1592/phco.22.3.188.33553/abstract |