Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia
Objective We evaluated the effect of chronic use of statins based on C-reactive protein (CRP) levels and hospital length of stay (LOS) in patients admitted with community-acquired pneumonia (CAP). Methods We conducted a retrospective study over 12 months at a teaching hospital in Lebanon comparing p...
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2020
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| Online Access: | http://hdl.handle.net/10725/12095 https://doi.org/10.1177/0300060520938586 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.sagepub.com/doi/full/10.1177/0300060520938586 |
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| _version_ | 1864513489699078144 |
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| author | Zeenny, Rony M. |
| author2 | Mansour, Hanine Kabbara, Wissam K. Chamoun, Nibal Audi, Myriam Yared, Yasmina Salameh, Pascale |
| author2_role | author author author author author author |
| author_facet | Zeenny, Rony M. Mansour, Hanine Kabbara, Wissam K. Chamoun, Nibal Audi, Myriam Yared, Yasmina Salameh, Pascale |
| author_role | author |
| dc.creator.none.fl_str_mv | Zeenny, Rony M. Mansour, Hanine Kabbara, Wissam K. Chamoun, Nibal Audi, Myriam Yared, Yasmina Salameh, Pascale |
| dc.date.none.fl_str_mv | 2020-08-29T13:18:25Z 2020-08-29T13:18:25Z 2020 2020-08-29 |
| dc.identifier.none.fl_str_mv | 0300-0605 http://hdl.handle.net/10725/12095 https://doi.org/10.1177/0300060520938586 Zeenny, R. M., Mansour, H., Kabbara, W. K., Chamoun, N., Audi, M., Yared, Y., & Salameh, P. (2020). Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia. Journal of International Medical Research, 48(8), 1-8. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.sagepub.com/doi/full/10.1177/0300060520938586 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Journal of International Medical Research |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Objective We evaluated the effect of chronic use of statins based on C-reactive protein (CRP) levels and hospital length of stay (LOS) in patients admitted with community-acquired pneumonia (CAP). Methods We conducted a retrospective study over 12 months at a teaching hospital in Lebanon comparing patients with CAP taking chronic statins with patients not taking statins. Included patients with CAP were older than age 18 years and had two CRP level measures during hospitalization. CURB-65 criteria were used to assess the severity of pneumonia. A decrease in CRP levels on days 1 and 3, LOS, and normalization of fever were used to assess the response to antibiotics. Results Sixty-one patients were taking statins and 90 patients were not taking statins. Patients on statins had significantly more comorbid conditions; both groups had comparable CURB-65 scores. In both groups, no statistically significant difference was seen for the decrease in CRP level on days 1 and 3 and LOS. No difference in days to normalization of fever was detected in either group. Conclusion No association was found between the chronic use of statins and CRP levels, LOS, or days to fever normalization in patients with CAP. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_20e8dc741ef040335e97425d9d4ae82a |
| identifier_str_mv | 0300-0605 Zeenny, R. M., Mansour, H., Kabbara, W. K., Chamoun, N., Audi, M., Yared, Y., & Salameh, P. (2020). Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia. Journal of International Medical Research, 48(8), 1-8. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/12095 |
| publishDate | 2020 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumoniaZeenny, Rony M.Mansour, HanineKabbara, Wissam K.Chamoun, NibalAudi, MyriamYared, YasminaSalameh, PascaleObjective We evaluated the effect of chronic use of statins based on C-reactive protein (CRP) levels and hospital length of stay (LOS) in patients admitted with community-acquired pneumonia (CAP). Methods We conducted a retrospective study over 12 months at a teaching hospital in Lebanon comparing patients with CAP taking chronic statins with patients not taking statins. Included patients with CAP were older than age 18 years and had two CRP level measures during hospitalization. CURB-65 criteria were used to assess the severity of pneumonia. A decrease in CRP levels on days 1 and 3, LOS, and normalization of fever were used to assess the response to antibiotics. Results Sixty-one patients were taking statins and 90 patients were not taking statins. Patients on statins had significantly more comorbid conditions; both groups had comparable CURB-65 scores. In both groups, no statistically significant difference was seen for the decrease in CRP level on days 1 and 3 and LOS. No difference in days to normalization of fever was detected in either group. Conclusion No association was found between the chronic use of statins and CRP levels, LOS, or days to fever normalization in patients with CAP.PublishedN/A2020-08-29T13:18:25Z2020-08-29T13:18:25Z20202020-08-29Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0300-0605http://hdl.handle.net/10725/12095https://doi.org/10.1177/0300060520938586Zeenny, R. M., Mansour, H., Kabbara, W. K., Chamoun, N., Audi, M., Yared, Y., & Salameh, P. (2020). Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia. Journal of International Medical Research, 48(8), 1-8.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://journals.sagepub.com/doi/full/10.1177/0300060520938586enJournal of International Medical Researchinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/120952022-03-03T14:16:37Z |
| spellingShingle | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia Zeenny, Rony M. |
| status_str | publishedVersion |
| title | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| title_full | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| title_fullStr | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| title_full_unstemmed | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| title_short | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| title_sort | Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia |
| url | http://hdl.handle.net/10725/12095 https://doi.org/10.1177/0300060520938586 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://journals.sagepub.com/doi/full/10.1177/0300060520938586 |