Metal-catalysed tandem metathesis-hydrogenation reactions for the synthesis of carba analogues of cyclic peptides

Dicarba cyclic peptide analogues of the cystine-containing octapeptides octreotide, lanreotide, and vapreotide, all known somatostatin analogues, have been synthesized via an on-resin homogeneous metal-catalysed sequence involving ruthenium-catalysed ring-closing metathesis followed by rhodium-catal...

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Bibliographic Details
Main Author: Elaridi, Jomana (author)
Other Authors: Whelan, Amanda N. (author), Mudler, Roger J. (author), Robinson, Andrea J. (author), Jackson, W. Roy (author)
Format: article
Published: 2005
Online Access:http://hdl.handle.net/10725/2868
http://dx.doi.org/10.1139/v05-100
http://www.nrcresearchpress.com/doi/abs/10.1139/v05-100#.V5XbcLh97cs
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