Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases
Liver resection is the preferred treatment for gastrointestinal stromal tumor liver metastases (GIST LMs) when complete resection can be achieved. Major and extended hepatic resections can be safely performed, and using modern techniques, an increasing proportion of patients with GIST LMs are candid...
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| Format: | article |
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2009
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| Online Access: | http://hdl.handle.net/10725/2609 http://dx.doi.org/10.1016/j.hoc.2008.11.001 http://www.sciencedirect.com/science/article/pii/S0889858808001731 |
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| _version_ | 1864513458713657344 |
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| author | Zalinski, Stephanie |
| author2 | Palavecino, Martin Abdalla, Eddie |
| author2_role | author author |
| author_facet | Zalinski, Stephanie Palavecino, Martin Abdalla, Eddie |
| author_role | author |
| dc.creator.none.fl_str_mv | Zalinski, Stephanie Palavecino, Martin Abdalla, Eddie |
| dc.date.none.fl_str_mv | 2009 2015-11-19T07:12:00Z 2015-11-19T07:12:00Z 2015-11-19 |
| dc.identifier.none.fl_str_mv | 0889-8588 http://hdl.handle.net/10725/2609 http://dx.doi.org/10.1016/j.hoc.2008.11.001 Zalinski, S., Palavecino, M., & Abdalla, E. K. (2009). Hepatic resection for gastrointestinal stromal tumor liver metastases. Hematology/oncology clinics of North America, 23(1), 115-127. http://www.sciencedirect.com/science/article/pii/S0889858808001731 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Hematology/Oncology Clinics of North America |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Liver resection is the preferred treatment for gastrointestinal stromal tumor liver metastases (GIST LMs) when complete resection can be achieved. Major and extended hepatic resections can be safely performed, and using modern techniques, an increasing proportion of patients with GIST LMs are candidates for potentially curative therapy. The combination of tyrosine kinase inhibitor therapy (eg, imatinib) with surgery seems to improve outcome, and although prospective data are lacking, a short neoadjuvant course (6 months) of imatinib therapy followed by resection may improve patient selection for surgery and outcome from treatment. Postoperative therapy with imatinib is generally advised, although the duration of such therapy is not yet clearly defined. These questions may formulate the basis for future prospective studies of imatinib with complete resection of GIST LMs. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_2770a2d17fde797d5d94a2cd00a1f6b7 |
| identifier_str_mv | 0889-8588 Zalinski, S., Palavecino, M., & Abdalla, E. K. (2009). Hepatic resection for gastrointestinal stromal tumor liver metastases. Hematology/oncology clinics of North America, 23(1), 115-127. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/2609 |
| publishDate | 2009 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Hepatic Resection for Gastrointestinal Stromal Tumor Liver MetastasesZalinski, StephaniePalavecino, MartinAbdalla, EddieLiver resection is the preferred treatment for gastrointestinal stromal tumor liver metastases (GIST LMs) when complete resection can be achieved. Major and extended hepatic resections can be safely performed, and using modern techniques, an increasing proportion of patients with GIST LMs are candidates for potentially curative therapy. The combination of tyrosine kinase inhibitor therapy (eg, imatinib) with surgery seems to improve outcome, and although prospective data are lacking, a short neoadjuvant course (6 months) of imatinib therapy followed by resection may improve patient selection for surgery and outcome from treatment. Postoperative therapy with imatinib is generally advised, although the duration of such therapy is not yet clearly defined. These questions may formulate the basis for future prospective studies of imatinib with complete resection of GIST LMs.PublishedN/A2015-11-19T07:12:00Z2015-11-19T07:12:00Z20092015-11-19Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0889-8588http://hdl.handle.net/10725/2609http://dx.doi.org/10.1016/j.hoc.2008.11.001Zalinski, S., Palavecino, M., & Abdalla, E. K. (2009). Hepatic resection for gastrointestinal stromal tumor liver metastases. Hematology/oncology clinics of North America, 23(1), 115-127.http://www.sciencedirect.com/science/article/pii/S0889858808001731enHematology/Oncology Clinics of North Americainfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/26092016-08-25T10:04:31Z |
| spellingShingle | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases Zalinski, Stephanie |
| status_str | publishedVersion |
| title | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| title_full | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| title_fullStr | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| title_full_unstemmed | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| title_short | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| title_sort | Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases |
| url | http://hdl.handle.net/10725/2609 http://dx.doi.org/10.1016/j.hoc.2008.11.001 http://www.sciencedirect.com/science/article/pii/S0889858808001731 |