Strain differences in systematic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier
We measured monoamine oxidase activity in the cerebral cortex, striatum and brain microvessels of two mouse strains that differ in their susceptibility to systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPIP) neurotoxicity using specific pargyline binding and the rate of MPTP oxidation ir. vi...
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| Main Author: | Riachi, Naji J. (author) |
|---|---|
| Other Authors: | Harik, Sami I. (author) |
| Format: | article |
| Published: |
1988
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| Online Access: | http://hdl.handle.net/10725/10427 https://doi.org/10.1016/0024-3205(88)90189-0 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/0024320588901890 |
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