Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites
Fluorescence, excitation, and emission spectra of some benzo[a]pyrene diols and diol epoxides in aqueous and non-aqueous media have been studied and ground- and excited-state dissociation constants have been determined. Spectral shifts due to changes in salvation, Stokes shifts, and pKa and pKa* val...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| التنسيق: | article |
| منشور في: |
1989
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/6350 http://dx.doi.org/10.1039/P29890000937 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://pubs.rsc.org/-/content/articlelanding/1989/p2/p29890000937/unauth#!divAbstract |
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| _version_ | 1864513479730266112 |
|---|---|
| author | Capomacchia, Anthony C. |
| author2 | Kumar, Vijay Jennings, Robert N. |
| author2_role | author author |
| author_facet | Capomacchia, Anthony C. Kumar, Vijay Jennings, Robert N. |
| author_role | author |
| dc.creator.none.fl_str_mv | Capomacchia, Anthony C. Kumar, Vijay Jennings, Robert N. |
| dc.date.none.fl_str_mv | 1989 2017-10-18T09:34:05Z 2017-10-18T09:34:05Z 2017-10-18 |
| dc.identifier.none.fl_str_mv | 1364-5471 http://hdl.handle.net/10725/6350 http://dx.doi.org/10.1039/P29890000937 Capomacchia, A. C., Kumar, V., & Jennings, R. N. (1989). Internal hydrogen bonding in benzo [a] pyrene diol and diol epoxide metabolites. Journal of the Chemical Society, Perkin Transactions 2, (8), 937-941. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://pubs.rsc.org/-/content/articlelanding/1989/p2/p29890000937/unauth#!divAbstract |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Chemical Society, Perkin Transactions 2 |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Fluorescence, excitation, and emission spectra of some benzo[a]pyrene diols and diol epoxides in aqueous and non-aqueous media have been studied and ground- and excited-state dissociation constants have been determined. Spectral shifts due to changes in salvation, Stokes shifts, and pKa and pKa* values are employed to show that the diols and diol epoxides possess an intramolecular hydrogen bond between ortho hydroxy groups when in non-aqueous media. In aqueous media no internal hydrogen bonding occurs either between ortho hydroxy groups or hydroxy and epoxide groups. The latter point is significant with regard to the carcinogenic reactivity of anti- and syn-7,8-dihydroxy 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_2aa72404b5c7374f5ea7cedbedbb9d91 |
| identifier_str_mv | 1364-5471 Capomacchia, A. C., Kumar, V., & Jennings, R. N. (1989). Internal hydrogen bonding in benzo [a] pyrene diol and diol epoxide metabolites. Journal of the Chemical Society, Perkin Transactions 2, (8), 937-941. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/6350 |
| publishDate | 1989 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolitesCapomacchia, Anthony C.Kumar, VijayJennings, Robert N.Fluorescence, excitation, and emission spectra of some benzo[a]pyrene diols and diol epoxides in aqueous and non-aqueous media have been studied and ground- and excited-state dissociation constants have been determined. Spectral shifts due to changes in salvation, Stokes shifts, and pKa and pKa* values are employed to show that the diols and diol epoxides possess an intramolecular hydrogen bond between ortho hydroxy groups when in non-aqueous media. In aqueous media no internal hydrogen bonding occurs either between ortho hydroxy groups or hydroxy and epoxide groups. The latter point is significant with regard to the carcinogenic reactivity of anti- and syn-7,8-dihydroxy 9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.PublishedN/A2017-10-18T09:34:05Z2017-10-18T09:34:05Z19892017-10-18Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1364-5471http://hdl.handle.net/10725/6350http://dx.doi.org/10.1039/P29890000937Capomacchia, A. C., Kumar, V., & Jennings, R. N. (1989). Internal hydrogen bonding in benzo [a] pyrene diol and diol epoxide metabolites. Journal of the Chemical Society, Perkin Transactions 2, (8), 937-941.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://pubs.rsc.org/-/content/articlelanding/1989/p2/p29890000937/unauth#!divAbstractenChemical Society, Perkin Transactions 2info:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/63502021-03-19T10:43:10Z |
| spellingShingle | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites Capomacchia, Anthony C. |
| status_str | publishedVersion |
| title | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| title_full | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| title_fullStr | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| title_full_unstemmed | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| title_short | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| title_sort | Internal hydrogen bonding in benzo[a]pyrene diol and diol epoxide metabolites |
| url | http://hdl.handle.net/10725/6350 http://dx.doi.org/10.1039/P29890000937 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://pubs.rsc.org/-/content/articlelanding/1989/p2/p29890000937/unauth#!divAbstract |