Inhibition of Tau filament formation by conformational modulation

Antiaggregation drugs play an important role in therapeutic approaches for Alzheimer’s disease. Although a large number of small molecules that inhibit the aggregation of the tau protein have been identified, little is known about their mode of action. Here, we reveal the mechanism and the nature of...

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Bibliographic Details
Main Author: Akoury, Elias (author)
Other Authors: Gajdat, Michal (author), Pickhardt, Marcus (author)
Format: article
Published: 2013
Online Access:http://hdl.handle.net/10725/10251
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://pubs.acs.org/doi/abs/10.1021/ja312471h
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