A photoactivatable chemotherapeutic Ru(II) complex bearing bathocuproine ligand efficiently induces cell death in human malignant melanoma cells through a multi-mechanistic pathway

Photoactivated chemotherapy (PACT) is an emerging strategy for targeted cancer therapy. Strained Ru complexes with pseudo-octahedral geometry may undergo photo-induced ligand dissociation, forming aquated photoproducts that are significantly more cytotoxic compared to the precursor complex. The comp...

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Bibliographic Details
Main Author: Elias, Maria George (author)
Other Authors: Mehanna, Stephanie (author), Elias, Elias (author), Khnayzer, Rony S. (author), Daher, Costantine F. (author)
Format: article
Published: 2021
Online Access:http://hdl.handle.net/10725/14375
https://doi.org/10.1016/j.cbi.2021.109644
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.sciencedirect.com/science/article/pii/S0009279721002829
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