DNA methylation at promoter regions regulates the timing of gene activation in xenopus laevis embryos

The levels of genomic DNA methylation in vertebrate species display a wide range of developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the amphibian, Xenopus laevis, is not subjected to active demethylation of 5-methyl cytosine immediately after fertilization. Hig...

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Bibliographic Details
Main Author: El Maarri, Osman (author)
Other Authors: Stancheva, Irina (author), Walter, Joern (author), Niveleau, Alain (author), Meehan, Richard R. (author)
Format: article
Published: 2002
Online Access:http://hdl.handle.net/10725/6166
https://doi.org/10.1006/dbio.2001.0560
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.sciencedirect.com/science/article/pii/S0012160601905603
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