Synthesis of new pyrazolo[3,4-d]pyrimidine derivatives and evaluation of their anti-inflammatory and anticancer activities

This study reports the synthesis of two series of new purine bioisosteres comprising a pyrazolo[3,4-d]pyrimidine scaffold linked to piperazine moiety through different amide linkages. The newly synthesized compounds were evaluated for anticancer activity against four cell lines (MDA-MB-231, MCF-7, S...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Abd El Razik, Heba A. (author)
مؤلفون آخرون: Mroueh, Mohamad (author), Faour, Wissam H. (author), Shebaby, Wassim N. (author), Daher, Costantine F. (author), Ashour, Hayam M. A. (author), Ragab, Hanan M. (author)
التنسيق: article
منشور في: 2017
الوصول للمادة أونلاين:http://hdl.handle.net/10725/5366
http://dx.doi.org/10.1111/cbdd.12929
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://onlinelibrary.wiley.com/doi/10.1111/cbdd.12929/full
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