Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies

Diabetic foot ulcers (DFUs) is a complication of diabetes that can impose great risk of morbidity and mortality. Classically, DFU treatment is based on local debridement, topical agents and non-surgical offloading. When compared to SC, conservative surgery (CS) has been reported to yield better resu...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Yammine, Kaissar (author)
مؤلفون آخرون: Assi, Chahine (author)
التنسيق: article
منشور في: 2019
الوصول للمادة أونلاين:http://hdl.handle.net/10725/10968
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3327358
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author Yammine, Kaissar
author2 Assi, Chahine
author2_role author
author_facet Yammine, Kaissar
Assi, Chahine
author_role author
dc.creator.none.fl_str_mv Yammine, Kaissar
Assi, Chahine
dc.date.none.fl_str_mv 2019-07-04T05:46:49Z
2019-07-04T05:46:49Z
2019
2019-07-04
dc.identifier.none.fl_str_mv http://hdl.handle.net/10725/10968
Yammine, K., & Assi, C. (2019). Conservative Surgery Versus Standard Care in Treating Neuropathic Plantar Forefoot Ulcers. A Meta-Analysis of Comparative Studies. A Meta-Analysis of Comparative Studies (January 31, 2019).
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3327358
dc.language.none.fl_str_mv en
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Diabetic foot ulcers (DFUs) is a complication of diabetes that can impose great risk of morbidity and mortality. Classically, DFU treatment is based on local debridement, topical agents and non-surgical offloading. When compared to SC, conservative surgery (CS) has been reported to yield better results for neuropathic wounds. We systematically reviewed studies published from inception to Oct 2018, assessed the methodological quality, and collate quantitative evidence on the outcomes of CS versus SC. Nine studies (2 randomized and 7 retrospective comparative) were included totalizing 436 ulcers (216 and 220 DFUs treated with SC and CS, respectively). Overall meta-analytical results showed significant better healing, recurrence and amputation/revision surgery rates following CS compared to SC. Subgroup analysis of infected ulcers (2 studies) reproduced the same for the first and last outcomes. Subgroup analysis for non-infected ulcers (7 studies) generated significant better results in favor of CS in all outcomes but transfer rate. This review demonstrated the superiority of conservative surgery over standard care in treating forefoot neuropathic wounds.
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identifier_str_mv Yammine, K., & Assi, C. (2019). Conservative Surgery Versus Standard Care in Treating Neuropathic Plantar Forefoot Ulcers. A Meta-Analysis of Comparative Studies. A Meta-Analysis of Comparative Studies (January 31, 2019).
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spelling Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studiesYammine, KaissarAssi, ChahineDiabetic foot ulcers (DFUs) is a complication of diabetes that can impose great risk of morbidity and mortality. Classically, DFU treatment is based on local debridement, topical agents and non-surgical offloading. When compared to SC, conservative surgery (CS) has been reported to yield better results for neuropathic wounds. We systematically reviewed studies published from inception to Oct 2018, assessed the methodological quality, and collate quantitative evidence on the outcomes of CS versus SC. Nine studies (2 randomized and 7 retrospective comparative) were included totalizing 436 ulcers (216 and 220 DFUs treated with SC and CS, respectively). Overall meta-analytical results showed significant better healing, recurrence and amputation/revision surgery rates following CS compared to SC. Subgroup analysis of infected ulcers (2 studies) reproduced the same for the first and last outcomes. Subgroup analysis for non-infected ulcers (7 studies) generated significant better results in favor of CS in all outcomes but transfer rate. This review demonstrated the superiority of conservative surgery over standard care in treating forefoot neuropathic wounds.Pre-printN/A2019-07-04T05:46:49Z2019-07-04T05:46:49Z20192019-07-04Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10725/10968Yammine, K., & Assi, C. (2019). Conservative Surgery Versus Standard Care in Treating Neuropathic Plantar Forefoot Ulcers. A Meta-Analysis of Comparative Studies. A Meta-Analysis of Comparative Studies (January 31, 2019).http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://papers.ssrn.com/sol3/papers.cfm?abstract_id=3327358eninfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/109682021-03-19T10:45:20Z
spellingShingle Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
Yammine, Kaissar
status_str publishedVersion
title Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
title_full Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
title_fullStr Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
title_full_unstemmed Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
title_short Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
title_sort Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
url http://hdl.handle.net/10725/10968
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3327358