Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer

Misfolding of the microtubule‐associated protein Tau is a hallmark of Alzheimer disease and several other neurodegenerative disorders. Because of the dynamic nature of the Tau protein, little is known about the changes in Tau structure that occur during misfolding. Here we studied the structural con...

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Bibliographic Details
Main Author: Akoury, Elias (author)
Other Authors: Mukrasch, Marco D. (author), Biernat, Jacek (author), Tepper, Katharina (author), Ozenne, Valery (author), Mandelkow, Eckhard (author), Blackedge, Martin (author), Zweckstetter, Markus (author)
Format: article
Published: 2016
Online Access:http://hdl.handle.net/10725/10254
https://doi.org/10.1002/pro.2911
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://onlinelibrary.wiley.com/doi/full/10.1002/pro.2911
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