Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects
We tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695–rs4506565–rs7903146–rs12243326–rs789534...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , |
| التنسيق: | article |
| منشور في: |
2012
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/10694 https://doi.org/10.1016/j.diabres.2012.09.044 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S0168822712003671 |
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| _version_ | 1864513487101755392 |
|---|---|
| author | Nemr, Rita |
| author2 | Turki, Amira Echtay, Akram Al-Zaben, Ghadeer S. Daher, Hoda S. Irani-Hakime, Nora A. Kelestian, Sose H. Almawi, Wassim Y. |
| author2_role | author author author author author author author |
| author_facet | Nemr, Rita Turki, Amira Echtay, Akram Al-Zaben, Ghadeer S. Daher, Hoda S. Irani-Hakime, Nora A. Kelestian, Sose H. Almawi, Wassim Y. |
| author_role | author |
| dc.creator.none.fl_str_mv | Nemr, Rita Turki, Amira Echtay, Akram Al-Zaben, Ghadeer S. Daher, Hoda S. Irani-Hakime, Nora A. Kelestian, Sose H. Almawi, Wassim Y. |
| dc.date.none.fl_str_mv | 2012 2019-05-29T09:05:08Z 2019-05-29T09:05:08Z 2019-05-29 |
| dc.identifier.none.fl_str_mv | 1872-8227 http://hdl.handle.net/10725/10694 https://doi.org/10.1016/j.diabres.2012.09.044 Nemr, R., Turki, A., Echtay, A., Al-Zaben, G. S., Daher, H. S., Irani-Hakime, N. A., ... & Almawi, W. Y. (2012). Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects. Diabetes research and clinical practice, 98(3), e23-e27. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S0168822712003671 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Diabetes Research and Clinical Practice |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | We tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695–rs4506565–rs7903146–rs12243326–rs7895340–rs11196205–rs12255372) identified positively- (2122112, 2222222) and negatively- (1111111) T2DM-associated haplotypes. TCF7L2 is a common T2DM candidate gene in Lebanese people. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_3995d1a511f97d1079ee8d29ad0b13fa |
| identifier_str_mv | 1872-8227 Nemr, R., Turki, A., Echtay, A., Al-Zaben, G. S., Daher, H. S., Irani-Hakime, N. A., ... & Almawi, W. Y. (2012). Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects. Diabetes research and clinical practice, 98(3), e23-e27. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/10694 |
| publishDate | 2012 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjectsNemr, RitaTurki, AmiraEchtay, AkramAl-Zaben, Ghadeer S.Daher, Hoda S.Irani-Hakime, Nora A.Kelestian, Sose H.Almawi, Wassim Y.We tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695–rs4506565–rs7903146–rs12243326–rs7895340–rs11196205–rs12255372) identified positively- (2122112, 2222222) and negatively- (1111111) T2DM-associated haplotypes. TCF7L2 is a common T2DM candidate gene in Lebanese people.PublishedN/A2019-05-29T09:05:08Z2019-05-29T09:05:08Z20122019-05-29Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1872-8227http://hdl.handle.net/10725/10694https://doi.org/10.1016/j.diabres.2012.09.044Nemr, R., Turki, A., Echtay, A., Al-Zaben, G. S., Daher, H. S., Irani-Hakime, N. A., ... & Almawi, W. Y. (2012). Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects. Diabetes research and clinical practice, 98(3), e23-e27.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.sciencedirect.com/science/article/pii/S0168822712003671enDiabetes Research and Clinical Practiceinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/106942021-03-19T10:45:23Z |
| spellingShingle | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects Nemr, Rita |
| status_str | publishedVersion |
| title | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| title_full | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| title_fullStr | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| title_full_unstemmed | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| title_short | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| title_sort | Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
| url | http://hdl.handle.net/10725/10694 https://doi.org/10.1016/j.diabres.2012.09.044 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S0168822712003671 |