PSA-activated proaerolysin as a prostate specific cancer therapy

Native proaerolysin is a channel-forming bacterial protoxin that is activated upon cleavage by host proteases such as furin. PRX302 is an engineered form of proaerolysin in which the furin cleavage site has been replaced with a sequence known to be preferred by the protease, prostate specific antige...

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Bibliographic Details
Main Author: Abi-Habib, Ralph (author)
Other Authors: Browning, Jeff L. (author), Singh, Ravibhushan (author), Carter, Carol (author), Ortiz, Janelle (author)
Format: conferenceObject
Published: 2006
Online Access:http://hdl.handle.net/10725/8051
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://cancerres.aacrjournals.org/content/66/8_Supplement/514.4.short
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