Chemical oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its in vivo metabolism in rat brain and liver

We investigated in vivo the metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the brain and liver of rats 45 min after the systemic administration of 50 mg/kg of the neurotoxin. The metabolites present in brain and liver extracts were identified through multiple analytical methods...

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Bibliographic Details
Main Author: Riachi, Naji J. (author)
Other Authors: Arora, Pramond K. (author), Sayre, Lawrence M. (author)
Format: article
Published: 1988
Online Access:http://hdl.handle.net/10725/10434
https://doi.org/10.1016/S0006-291X(88)80432-7
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.sciencedirect.com/science/article/pii/S0006291X88804327
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