Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm
Stents play an important role in management of cerebral aneurysms. A stent reconstructs the parent artery, assists coil embolization, and decreases flow activity within an aneurysm. However, an in-stent stenosis often occurs within the stented artery and compromises the circulation at the parent art...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| التنسيق: | article |
| منشور في: |
2011
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/11013 https://doi.org/10.1016/j.medengphy.2010.12.013 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S1350453310003000#aep-keywords-id15 |
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| _version_ | 1864513487961587712 |
|---|---|
| author | Jou, Liang-Der |
| author2 | Mawad, Michel E. |
| author2_role | author |
| author_facet | Jou, Liang-Der Mawad, Michel E. |
| author_role | author |
| dc.creator.none.fl_str_mv | Jou, Liang-Der Mawad, Michel E. |
| dc.date.none.fl_str_mv | 2011 2019-07-09T09:16:00Z 2019-07-09T09:16:00Z 2019-07-09 |
| dc.identifier.none.fl_str_mv | 1873-4030 http://hdl.handle.net/10725/11013 https://doi.org/10.1016/j.medengphy.2010.12.013 Jou, L. D., & Mawad, M. E. (2011). Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm. Medical engineering & physics, 33(5), 573-580. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S1350453310003000#aep-keywords-id15 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Medical Engineering & Physics |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Stents play an important role in management of cerebral aneurysms. A stent reconstructs the parent artery, assists coil embolization, and decreases flow activity within an aneurysm. However, an in-stent stenosis often occurs within the stented artery and compromises the circulation at the parent artery. Hemodynamic basis of re-stenoses from aneurysm stenting is not fully understood. An 8 mm cavernous carotid aneurysm with a wide neck was treated by a Neuroform stent first and by coils five weeks later. A comparison of the difference in morphology during this five-week period reveals the presence of intimal hyperplasia in the internal carotid artery, 1.3 mm thick at the proximal end and 1 mm at the distal end of the stent, and 1 mm thick thrombus at the postero-inferior side of the aneurysm. Computational fluid dynamic analyses show that the site of intimal hyperplasia is exposed to low wall shear with high oscillatory shear index (OSI), and the location of thrombus is subject to high OSI. Intimal hyperplasia and thrombus occur at comparable rates, but at different hemodynamic conditions; however, both prefer regions with high OSIs. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_4602f964a95be77799fbff5b4f1850cc |
| identifier_str_mv | 1873-4030 Jou, L. D., & Mawad, M. E. (2011). Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm. Medical engineering & physics, 33(5), 573-580. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/11013 |
| publishDate | 2011 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysmJou, Liang-DerMawad, Michel E.Stents play an important role in management of cerebral aneurysms. A stent reconstructs the parent artery, assists coil embolization, and decreases flow activity within an aneurysm. However, an in-stent stenosis often occurs within the stented artery and compromises the circulation at the parent artery. Hemodynamic basis of re-stenoses from aneurysm stenting is not fully understood. An 8 mm cavernous carotid aneurysm with a wide neck was treated by a Neuroform stent first and by coils five weeks later. A comparison of the difference in morphology during this five-week period reveals the presence of intimal hyperplasia in the internal carotid artery, 1.3 mm thick at the proximal end and 1 mm at the distal end of the stent, and 1 mm thick thrombus at the postero-inferior side of the aneurysm. Computational fluid dynamic analyses show that the site of intimal hyperplasia is exposed to low wall shear with high oscillatory shear index (OSI), and the location of thrombus is subject to high OSI. Intimal hyperplasia and thrombus occur at comparable rates, but at different hemodynamic conditions; however, both prefer regions with high OSIs.PublishedN/A2019-07-09T09:16:00Z2019-07-09T09:16:00Z20112019-07-09Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1873-4030http://hdl.handle.net/10725/11013https://doi.org/10.1016/j.medengphy.2010.12.013Jou, L. D., & Mawad, M. E. (2011). Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm. Medical engineering & physics, 33(5), 573-580.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.sciencedirect.com/science/article/pii/S1350453310003000#aep-keywords-id15enMedical Engineering & Physicsinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/110132021-03-19T10:45:20Z |
| spellingShingle | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm Jou, Liang-Der |
| status_str | publishedVersion |
| title | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| title_full | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| title_fullStr | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| title_full_unstemmed | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| title_short | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| title_sort | Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm |
| url | http://hdl.handle.net/10725/11013 https://doi.org/10.1016/j.medengphy.2010.12.013 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/S1350453310003000#aep-keywords-id15 |