Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. Mononuclear cells and CD34+ blasts were not sensitive demonstrating the selectivity of HuArgI(Co)-PEG5000-induced arginine deprivation....
محفوظ في:
| المؤلف الرئيسي: | Bekdash, Amira (author) |
|---|---|
| مؤلفون آخرون: | Abi-Habib, Ralph J. (author), Tanios, Rita (author), Stone, Everett (author), Georgiou, Georges (author), Frankel, Arthur E. (author), Kassab, Elias (author) |
| التنسيق: | article |
| منشور في: |
2013
|
| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/2741 http://dx.doi.org/10.1016/j.leukres.2013.08.007 http://www.sciencedirect.com/science/article/pii/S0145212613002889 |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
مواد مشابهة
-
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells
حسب: Khoury, Oula
منشور في: (2015) -
Human Recombinant Arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Leads to Autophagy-Dependent Cell Death in Prostate Cancer Cells
حسب: Chehab, Lemir Malek
منشور في: (2024) -
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
حسب: Abdel Khalek, Maya
منشور في: (2021) -
Decoding the Therapeutic Potential of [HuArgI (Co)-PEG5000] Arginase Treatment
حسب: Zeineddine, Mira
منشور في: (2023) -
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
حسب: El Jawhari, Yassmine
منشور في: (2018)