Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome

Objective: The objective of this study is to assess the effect of two methods of vaginal scrubbing before egg retrieval on the outcome of in vitro fertilization-embryo transfer (IVF-ET) cycles. Method: 721 consecutive cycles of IVF-ET, at the American University Hospital of Beirut, were randomized p...

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Main Author: Zreik, Tony (author)
Other Authors: Hannoun, A. (author), Awwad, J. (author), Ghaziri, G. (author), Abu-Musa, A. (author)
Format: article
Published: 2008
Online Access:http://hdl.handle.net/10725/2309
http://dx.doi.org/10.1159/000156378
http://www.karger.com/Article/Abstract/156378
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author Zreik, Tony
author2 Hannoun, A.
Awwad, J.
Ghaziri, G.
Abu-Musa, A.
author2_role author
author
author
author
author_facet Zreik, Tony
Hannoun, A.
Awwad, J.
Ghaziri, G.
Abu-Musa, A.
author_role author
dc.creator.none.fl_str_mv Zreik, Tony
Hannoun, A.
Awwad, J.
Ghaziri, G.
Abu-Musa, A.
dc.date.none.fl_str_mv 2008
2015-10-22T12:07:10Z
2015-10-22T12:07:10Z
2015-10-22
dc.identifier.none.fl_str_mv 0378-7346
http://hdl.handle.net/10725/2309
http://dx.doi.org/10.1159/000156378
Hannoun, A., Awwad, J., Zreik, T., Ghaziri, G., & Abu-Musa, A. (2008). Effect of betadine vaginal preparation during oocyte aspiration in in vitro fertilization cycles on pregnancy outcome. Gynecologic and obstetric investigation, 66(4), 274-278.
http://www.karger.com/Article/Abstract/156378
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Gynecologic and obstetric investigation
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Objective: The objective of this study is to assess the effect of two methods of vaginal scrubbing before egg retrieval on the outcome of in vitro fertilization-embryo transfer (IVF-ET) cycles. Method: 721 consecutive cycles of IVF-ET, at the American University Hospital of Beirut, were randomized prospectively into one of two groups. In the study group the betadine used to scrub the vagina, prior to egg retrieval, was not washed out, whereas in the control group this betadine was cleansed by saline irrigation. The two groups were compared as to the outcome of their IVF-ET cycles. Result: Both groups were similar in age, mean dose of FSH received, the number of oocytes and embryos obtained, the number of grade 1 embryos obtained, and the fertilization rate. There was no difference in the total pregnancy, clinical pregnancy, missed abortion, and multiple pregnancy rates between the two groups. However, the chemical pregnancy rate was higher in the study group as compared to controls. Conclusion: Vaginal preparation by betadine does not seem to affect the results of IVF. However, because it is associated with an increase in the rate of chemical pregnancy, it is advisable to cleanse before oocyte aspiration.
eu_rights_str_mv openAccess
format article
id LAURepo_4bf678fa27238e845c8575da2dda245e
identifier_str_mv 0378-7346
Hannoun, A., Awwad, J., Zreik, T., Ghaziri, G., & Abu-Musa, A. (2008). Effect of betadine vaginal preparation during oocyte aspiration in in vitro fertilization cycles on pregnancy outcome. Gynecologic and obstetric investigation, 66(4), 274-278.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/2309
publishDate 2008
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
spelling Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy OutcomeZreik, TonyHannoun, A.Awwad, J.Ghaziri, G.Abu-Musa, A.Objective: The objective of this study is to assess the effect of two methods of vaginal scrubbing before egg retrieval on the outcome of in vitro fertilization-embryo transfer (IVF-ET) cycles. Method: 721 consecutive cycles of IVF-ET, at the American University Hospital of Beirut, were randomized prospectively into one of two groups. In the study group the betadine used to scrub the vagina, prior to egg retrieval, was not washed out, whereas in the control group this betadine was cleansed by saline irrigation. The two groups were compared as to the outcome of their IVF-ET cycles. Result: Both groups were similar in age, mean dose of FSH received, the number of oocytes and embryos obtained, the number of grade 1 embryos obtained, and the fertilization rate. There was no difference in the total pregnancy, clinical pregnancy, missed abortion, and multiple pregnancy rates between the two groups. However, the chemical pregnancy rate was higher in the study group as compared to controls. Conclusion: Vaginal preparation by betadine does not seem to affect the results of IVF. However, because it is associated with an increase in the rate of chemical pregnancy, it is advisable to cleanse before oocyte aspiration.PublishedN/A2015-10-22T12:07:10Z2015-10-22T12:07:10Z20082015-10-22Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0378-7346http://hdl.handle.net/10725/2309http://dx.doi.org/10.1159/000156378Hannoun, A., Awwad, J., Zreik, T., Ghaziri, G., & Abu-Musa, A. (2008). Effect of betadine vaginal preparation during oocyte aspiration in in vitro fertilization cycles on pregnancy outcome. Gynecologic and obstetric investigation, 66(4), 274-278.http://www.karger.com/Article/Abstract/156378enGynecologic and obstetric investigationinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/23092019-02-28T09:54:16Z
spellingShingle Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
Zreik, Tony
status_str publishedVersion
title Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
title_full Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
title_fullStr Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
title_full_unstemmed Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
title_short Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
title_sort Effect of Betadine Vaginal Preparation during Oocyte Aspiration in in vitro Fertilization Cycles on Pregnancy Outcome
url http://hdl.handle.net/10725/2309
http://dx.doi.org/10.1159/000156378
http://www.karger.com/Article/Abstract/156378