Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis
Benign recurrent intrahepatic cholestasis (BRIC) is a syndrome characterized by recurrent episodes of cholestasis with associated pruritus. The intensity and duration of cholestatic episodes, and the length of the intervening periods, vary. unpredictably. We report the case of a patient with BRIC wh...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , |
| التنسيق: | article |
| منشور في: |
1996
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/10704 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://pubmed.ncbi.nlm.nih.gov/8855752/ |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513487117484032 |
|---|---|
| author | Chatila, R. |
| author2 | Bergasa, N. V. Lagarde, S. West, A. B. |
| author2_role | author author author |
| author_facet | Chatila, R. Bergasa, N. V. Lagarde, S. West, A. B. |
| author_role | author |
| dc.creator.none.fl_str_mv | Chatila, R. Bergasa, N. V. Lagarde, S. West, A. B. |
| dc.date.none.fl_str_mv | 1996 2019-05-30T09:00:28Z 2019-05-30T09:00:28Z 2019-05-30 |
| dc.identifier.none.fl_str_mv | 1572-0241 http://hdl.handle.net/10725/10704 Chatila, R., Bergasa, N. V., Lagarde, S., & West, A. B. (1996). Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis. The American Journal of Gastroenterology, 91(10), 2215-2219. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://pubmed.ncbi.nlm.nih.gov/8855752/ |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | American Journal of Gastroenterology |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Benign recurrent intrahepatic cholestasis (BRIC) is a syndrome characterized by recurrent episodes of cholestasis with associated pruritus. The intensity and duration of cholestatic episodes, and the length of the intervening periods, vary. unpredictably. We report the case of a patient with BRIC who was incapacitated by a severe intractable cough that accompanied marked pruritus during her second cholestatic episode. No cause for the cough was found, and it resolved spontaneously with amelioration of mild restrictive abnormalities of pulmonary function as the cholestasis subsided. Although cough has not been recognized as a complication of cholestasis, we postulate that it may occur either (i) as a result of direct stimulation of sensory nerves by circulating humoral substances related to the cholestasis that act either peripherally in the airways or centrally, or (ii) through stimulation of the vagus nerve in the liver, leading to cough that is mediated either centrally or by reflex. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_5031acffce7c2b147c34e6fa1ea6fa42 |
| identifier_str_mv | 1572-0241 Chatila, R., Bergasa, N. V., Lagarde, S., & West, A. B. (1996). Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis. The American Journal of Gastroenterology, 91(10), 2215-2219. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/10704 |
| publishDate | 1996 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasisChatila, R.Bergasa, N. V.Lagarde, S.West, A. B.Benign recurrent intrahepatic cholestasis (BRIC) is a syndrome characterized by recurrent episodes of cholestasis with associated pruritus. The intensity and duration of cholestatic episodes, and the length of the intervening periods, vary. unpredictably. We report the case of a patient with BRIC who was incapacitated by a severe intractable cough that accompanied marked pruritus during her second cholestatic episode. No cause for the cough was found, and it resolved spontaneously with amelioration of mild restrictive abnormalities of pulmonary function as the cholestasis subsided. Although cough has not been recognized as a complication of cholestasis, we postulate that it may occur either (i) as a result of direct stimulation of sensory nerves by circulating humoral substances related to the cholestasis that act either peripherally in the airways or centrally, or (ii) through stimulation of the vagus nerve in the liver, leading to cough that is mediated either centrally or by reflex.PublishedN/A2019-05-30T09:00:28Z2019-05-30T09:00:28Z19962019-05-30Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1572-0241http://hdl.handle.net/10725/10704Chatila, R., Bergasa, N. V., Lagarde, S., & West, A. B. (1996). Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis. The American Journal of Gastroenterology, 91(10), 2215-2219.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://pubmed.ncbi.nlm.nih.gov/8855752/enAmerican Journal of Gastroenterologyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/107042024-05-17T13:16:23Z |
| spellingShingle | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis Chatila, R. |
| status_str | publishedVersion |
| title | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| title_full | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| title_fullStr | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| title_full_unstemmed | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| title_short | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| title_sort | Intractable cough and abnormal pulmonary function in benign recurrent intrahepatic cholestasis |
| url | http://hdl.handle.net/10725/10704 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://pubmed.ncbi.nlm.nih.gov/8855752/ |