Effect of Anthrax Lethal Toxin on Activation of MAPK Pathway and Autophagy in AML Cell Lines
Anthrax lethal toxin is an A-B toxin consisting of protective antigen (PrAg), the cell binding and translocation domain, and lethal factor (LF), the catalytic domain, which cleaves all mitogen-activated protein/extracellular regulated kinase kinases (MEKs), leading to the inhibition of the MAPK path...
Saved in:
| Main Author: | Soukarieh, Rania (author) |
|---|---|
| Format: | masterThesis |
| Published: |
2021
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10725/13700 https://doi.org/10.26756/th.2022.214 http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sensitivity of colorectal cancer cells to the recombinant Anthrax lethal toxin and the Urokinase-activated Anthrax lethal toxin. (c2014)
by: Kasbo, Zein Jean
Published: (2014) -
Mechanisms of Cytotoxicity of Wild-Type Anthrax Lethal Toxin (PrAg/LF) to Acute Myeloid Leukemia Cells: The role of Autophagy
by: Sarout, Diamo
Published: (2024) -
Sensitivity of acute myeloid leukemia cell lines to the dual targeting of the urokinase system and the mapk pathway by modified anthrax toxins. (c2010)
by: Timsah, Zahra S.
Published: (2010) -
Sensitivity of acute myeloid leukemia cells to the dual targeting of the urokinase plasminogen activator and the MAPK pathway by a urokinase-activated anthrax lethal toxin. (c2013)
by: Bekdash, Amira
Published: (2013) -
Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breast Cancer
by: Basala, Sobhiya
Published: (2023)