Characterization of urokinase plasminogen activator-activated recombinant anthrax toxin for targeted cancer therapy

Anthrax lethal toxin (LeTx), secreted by Bacillus anthracis, consists of protective antigen (PrAg) and lethal factor (LF). Following binding to its ubiquitously expressed cell surface receptors tumor endothelium marker 8 and capillary morphogenesis gene-2, PrAg is cleaved by cell-surface furin and f...

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Bibliographic Details
Main Author: Abi-Habib, Ralph J. (author)
Other Authors: Singh, Ravibhushan (author), Duesbery, Nicholas S. (author), Liu, Shihui (author), Bugge, Thomas H. (author), Leppla, Stephen H. (author)
Format: conferenceObject
Published: 2006
Online Access:http://hdl.handle.net/10725/8053
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://cancerres.aacrjournals.org/content/66/8_Supplement/712.4.short
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