The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3

The total number, morbidity and mortality attributed to viraemic hepatitis C virus (HCV) infections change over time making it difficult to compare reported estimates from different years. Models were developed for 15 countries to quantify and characterize the viraemic population and forecast the ch...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mokhbat, J. E. (author)
مؤلفون آخرون: Sibley, A. (author), Han, K. H. (author), Abourached, A. (author), Lesmana, L. A. (author), Makara, M. (author), Jafri, W. (author), Salupere, R. (author), Assiri, A. M (author)
التنسيق: article
منشور في: 2015
الوصول للمادة أونلاين:http://hdl.handle.net/10725/5211
http://dx.doi.org/10.1111/jvh.12476
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://onlinelibrary.wiley.com/doi/10.1111/jvh.12476/full
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author Mokhbat, J. E.
author2 Sibley, A.
Han, K. H.
Abourached, A.
Lesmana, L. A.
Makara, M.
Jafri, W.
Salupere, R.
Assiri, A. M
author2_role author
author
author
author
author
author
author
author
author_facet Mokhbat, J. E.
Sibley, A.
Han, K. H.
Abourached, A.
Lesmana, L. A.
Makara, M.
Jafri, W.
Salupere, R.
Assiri, A. M
author_role author
dc.creator.none.fl_str_mv Mokhbat, J. E.
Sibley, A.
Han, K. H.
Abourached, A.
Lesmana, L. A.
Makara, M.
Jafri, W.
Salupere, R.
Assiri, A. M
dc.date.none.fl_str_mv 2015
2017-02-10T13:54:06Z
2017-02-10T13:54:06Z
2017-02-10
dc.identifier.none.fl_str_mv 1352-0504
http://hdl.handle.net/10725/5211
http://dx.doi.org/10.1111/jvh.12476
Sibley, A., Han, K. H., Abourached, A., Lesmana, L. A., Makara, M., Jafri, W., ... & Abbas, Z. (2015). The present and future disease burden of hepatitis C virus infections with today's treatment paradigm–volume 3. Journal of viral hepatitis, 22(S4), 21-41.
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://onlinelibrary.wiley.com/doi/10.1111/jvh.12476/full
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Journal of Viral Hepatitis
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description The total number, morbidity and mortality attributed to viraemic hepatitis C virus (HCV) infections change over time making it difficult to compare reported estimates from different years. Models were developed for 15 countries to quantify and characterize the viraemic population and forecast the changes in the infected population and the corresponding disease burden from 2014 to 2030. With the exception of Iceland, Iran, Latvia and Pakistan, the total number of viraemic HCV infections is expected to decline from 2014 to 2030, but the associated morbidity and mortality are expected to increase in all countries except for Japan and South Korea. In the latter two countries, mortality due to an ageing population will drive down prevalence, morbidity and mortality. On the other hand, both countries have already experienced a rapid increase in HCV-related mortality and morbidity. HCV-related morbidity and mortality are projected to increase between 2014 and 2030 in all other countries as result of an ageing HCV-infected population. Thus, although the total number of HCV countries is expected to decline in most countries studied, the associated disease burden is expected to increase. The current treatment paradigm is inadequate if large reductions in HCV-related morbidity and mortality are to be achieved.
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identifier_str_mv 1352-0504
Sibley, A., Han, K. H., Abourached, A., Lesmana, L. A., Makara, M., Jafri, W., ... & Abbas, Z. (2015). The present and future disease burden of hepatitis C virus infections with today's treatment paradigm–volume 3. Journal of viral hepatitis, 22(S4), 21-41.
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spelling The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3Mokhbat, J. E.Sibley, A.Han, K. H.Abourached, A.Lesmana, L. A.Makara, M.Jafri, W.Salupere, R.Assiri, A. MThe total number, morbidity and mortality attributed to viraemic hepatitis C virus (HCV) infections change over time making it difficult to compare reported estimates from different years. Models were developed for 15 countries to quantify and characterize the viraemic population and forecast the changes in the infected population and the corresponding disease burden from 2014 to 2030. With the exception of Iceland, Iran, Latvia and Pakistan, the total number of viraemic HCV infections is expected to decline from 2014 to 2030, but the associated morbidity and mortality are expected to increase in all countries except for Japan and South Korea. In the latter two countries, mortality due to an ageing population will drive down prevalence, morbidity and mortality. On the other hand, both countries have already experienced a rapid increase in HCV-related mortality and morbidity. HCV-related morbidity and mortality are projected to increase between 2014 and 2030 in all other countries as result of an ageing HCV-infected population. Thus, although the total number of HCV countries is expected to decline in most countries studied, the associated disease burden is expected to increase. The current treatment paradigm is inadequate if large reductions in HCV-related morbidity and mortality are to be achieved.PublishedN/A2017-02-10T13:54:06Z2017-02-10T13:54:06Z20152017-02-10Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1352-0504http://hdl.handle.net/10725/5211http://dx.doi.org/10.1111/jvh.12476Sibley, A., Han, K. H., Abourached, A., Lesmana, L. A., Makara, M., Jafri, W., ... & Abbas, Z. (2015). The present and future disease burden of hepatitis C virus infections with today's treatment paradigm–volume 3. Journal of viral hepatitis, 22(S4), 21-41.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://onlinelibrary.wiley.com/doi/10.1111/jvh.12476/fullenJournal of Viral Hepatitisinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/52112021-03-19T10:00:56Z
spellingShingle The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
Mokhbat, J. E.
status_str publishedVersion
title The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
title_full The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
title_fullStr The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
title_full_unstemmed The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
title_short The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
title_sort The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
url http://hdl.handle.net/10725/5211
http://dx.doi.org/10.1111/jvh.12476
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://onlinelibrary.wiley.com/doi/10.1111/jvh.12476/full