Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies
The discovery of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity stimulated intense interest in neurotoxicology and in the possible toxic etiology of Parkinson's disease. Better understanding of MPTP neurotoxicity may be achieved by studies using 18F-radiolabeled MPTP analogs and p...
محفوظ في:
| المؤلف الرئيسي: | Riachi, N.J. (author) |
|---|---|
| مؤلفون آخرون: | Harik, S.I. (author), Hritz, M.A. (author), Berridge, M.S. (author), Sayre, L.M. (author) |
| التنسيق: | article |
| منشور في: |
1993
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/10440 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://jpet.aspetjournals.org/content/266/2/790.short |
| الوسوم: |
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مواد مشابهة
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Potent neurotoxic fluorinated 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine analogs as potential probes in models of parkinson disease
حسب: Riachi, Naji J.
منشور في: (1988) -
Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain
حسب: Riachi, N.J.
منشور في: (1989) -
Chemical oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its in vivo metabolism in rat brain and liver
حسب: Riachi, Naji J.
منشور في: (1988) -
On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. II. Susceptibility among mammalian species correlates with the toxin's metabolic patterns in brain microvessels and liver
حسب: Riachi, N.J.
منشور في: (1988) -
Strain differences in systematic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier
حسب: Riachi, Naji J.
منشور في: (1988)