Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development
Cleft lip and/or palate (CL/P) affects on average 1 in 700 live births and is considered to be the most common congenital craniofacial birth defect (Setó-Salvia and Stanier 2014). It results from a failure in the lip buds and/or palatal shelves to properly position, proliferate, migrate, or fuse (Bu...
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| Format: | masterThesis |
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2021
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| Online Access: | http://hdl.handle.net/10725/13690 https://doi.org/10.26756/th.2022.224 http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php |
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