Hemodynamic relationship between intracranial aneurysm and carotid stenosis
Objective: Coexistence of both an intracranial aneurysm and a stenosis at the same internal carotid artery is infrequent, but it may complicate therapeutic management of either disease. It is unclear if a stenosis plays any role in development of intracranial aneurysms. We study patients with intrac...
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2013
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| Online Access: | http://hdl.handle.net/10725/11023 https://doi.org/10.1179/016164110X12681290831522 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.tandfonline.com/doi/abs/10.1179/016164110X12681290831522 |
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| _version_ | 1864513487976267776 |
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| author | Jou, Liang-Der |
| author2 | Shaltoni, Hashem M. Morsi, Hesham Mawad, Michel E. |
| author2_role | author author author |
| author_facet | Jou, Liang-Der Shaltoni, Hashem M. Morsi, Hesham Mawad, Michel E. |
| author_role | author |
| dc.creator.none.fl_str_mv | Jou, Liang-Der Shaltoni, Hashem M. Morsi, Hesham Mawad, Michel E. |
| dc.date.none.fl_str_mv | 2013 2019-07-10T06:00:22Z 2019-07-10T06:00:22Z 2019-07-10 |
| dc.identifier.none.fl_str_mv | 1743-1328 http://hdl.handle.net/10725/11023 https://doi.org/10.1179/016164110X12681290831522 Jou, L. D., Shaltoni, H. M., Morsi, H., & Mawad, M. E. (2010). Hemodynamic relationship between intracranial aneurysm and carotid stenosis: review of clinical cases and numerical analyses. Neurological research, 32(10), 1083-1089. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.tandfonline.com/doi/abs/10.1179/016164110X12681290831522 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Neurological Research |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Hemodynamic relationship between intracranial aneurysm and carotid stenosis review of clinical cases and numerical analyses |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Objective: Coexistence of both an intracranial aneurysm and a stenosis at the same internal carotid artery is infrequent, but it may complicate therapeutic management of either disease. It is unclear if a stenosis plays any role in development of intracranial aneurysms. We study patients with intracranial aneurysms at our hospital and investigate if there is a relationship between a carotid stenosis and an intracranial aneurysm. Methods: Two hundred and nine patients who were treated for their intracranial aneurysms in a 2-year period were reviewed. Fifty-four patients were found to have at least one intracranial aneurysm and one intracranial or extracranial carotid stenosis. Ten of them had bilateral stenoses; 17 aneurysms were on the ipsilateral side of the stenosis, and eight on the contralateral side. Nineteen aneurysms were elsewhere. Two cases were selected for detailed computational fluid dynamics (CFD) analyses: one with an intracranial and the other with an extracranial stenosis. Results: Aneurysms on the contralateral side of a carotid stenosis are significantly larger than those aneurysms on the ipsilateral side or with bilateral stenoses (13.6 versus 6.6 mm; P < 0.01). CFD studies show that wall shear stress at the aneurysm is more likely affected by an adjacent intracranial stenosis than by an extracranial stenosis. Conclusions: Intracranial carotid aneurysms contralateral to a carotid stenosis are significantly larger than aneurysms with a carotid stenosis elsewhere. Rupture can occur on aneurysms with an extracranial carotid stenosis on the contralateral side or with an intracranial carotid stenosis on the ipsilateral side. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_5e8ff55993d32e2a328ded636e3e676e |
| identifier_str_mv | 1743-1328 Jou, L. D., Shaltoni, H. M., Morsi, H., & Mawad, M. E. (2010). Hemodynamic relationship between intracranial aneurysm and carotid stenosis: review of clinical cases and numerical analyses. Neurological research, 32(10), 1083-1089. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/11023 |
| publishDate | 2013 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Hemodynamic relationship between intracranial aneurysm and carotid stenosisreview of clinical cases and numerical analysesJou, Liang-DerShaltoni, Hashem M.Morsi, HeshamMawad, Michel E.Objective: Coexistence of both an intracranial aneurysm and a stenosis at the same internal carotid artery is infrequent, but it may complicate therapeutic management of either disease. It is unclear if a stenosis plays any role in development of intracranial aneurysms. We study patients with intracranial aneurysms at our hospital and investigate if there is a relationship between a carotid stenosis and an intracranial aneurysm. Methods: Two hundred and nine patients who were treated for their intracranial aneurysms in a 2-year period were reviewed. Fifty-four patients were found to have at least one intracranial aneurysm and one intracranial or extracranial carotid stenosis. Ten of them had bilateral stenoses; 17 aneurysms were on the ipsilateral side of the stenosis, and eight on the contralateral side. Nineteen aneurysms were elsewhere. Two cases were selected for detailed computational fluid dynamics (CFD) analyses: one with an intracranial and the other with an extracranial stenosis. Results: Aneurysms on the contralateral side of a carotid stenosis are significantly larger than those aneurysms on the ipsilateral side or with bilateral stenoses (13.6 versus 6.6 mm; P < 0.01). CFD studies show that wall shear stress at the aneurysm is more likely affected by an adjacent intracranial stenosis than by an extracranial stenosis. Conclusions: Intracranial carotid aneurysms contralateral to a carotid stenosis are significantly larger than aneurysms with a carotid stenosis elsewhere. Rupture can occur on aneurysms with an extracranial carotid stenosis on the contralateral side or with an intracranial carotid stenosis on the ipsilateral side.PublishedN/A2019-07-10T06:00:22Z2019-07-10T06:00:22Z20132019-07-10Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1743-1328http://hdl.handle.net/10725/11023https://doi.org/10.1179/016164110X12681290831522Jou, L. D., Shaltoni, H. M., Morsi, H., & Mawad, M. E. (2010). Hemodynamic relationship between intracranial aneurysm and carotid stenosis: review of clinical cases and numerical analyses. Neurological research, 32(10), 1083-1089.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.tandfonline.com/doi/abs/10.1179/016164110X12681290831522enNeurological Researchinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/110232021-03-19T10:45:26Z |
| spellingShingle | Hemodynamic relationship between intracranial aneurysm and carotid stenosis Jou, Liang-Der |
| status_str | publishedVersion |
| title | Hemodynamic relationship between intracranial aneurysm and carotid stenosis |
| title_full | Hemodynamic relationship between intracranial aneurysm and carotid stenosis |
| title_fullStr | Hemodynamic relationship between intracranial aneurysm and carotid stenosis |
| title_full_unstemmed | Hemodynamic relationship between intracranial aneurysm and carotid stenosis |
| title_short | Hemodynamic relationship between intracranial aneurysm and carotid stenosis |
| title_sort | Hemodynamic relationship between intracranial aneurysm and carotid stenosis |
| url | http://hdl.handle.net/10725/11023 https://doi.org/10.1179/016164110X12681290831522 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.tandfonline.com/doi/abs/10.1179/016164110X12681290831522 |