Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia

Purpose To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy. Patients and methods Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and...

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Main Author: Alshahrani, Saeed T. (author)
Other Authors: Ghazi, Nicola G. (author), Al-Rashaed, Saba (author)
Format: article
Published: 2016
Online Access:http://hdl.handle.net/10725/10831
https://doi.org/10.2147/OPTH.S91444
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697790/
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author Alshahrani, Saeed T.
author2 Ghazi, Nicola G.
Al-Rashaed, Saba
author2_role author
author
author_facet Alshahrani, Saeed T.
Ghazi, Nicola G.
Al-Rashaed, Saba
author_role author
dc.creator.none.fl_str_mv Alshahrani, Saeed T.
Ghazi, Nicola G.
Al-Rashaed, Saba
dc.date.none.fl_str_mv 2016
2019-06-14T11:36:23Z
2019-06-14T11:36:23Z
2019-06-14
dc.identifier.none.fl_str_mv 1177-5483
http://hdl.handle.net/10725/10831
https://doi.org/10.2147/OPTH.S91444
Alshahrani, S. T., Ghazi, N. G., & Al-Rashaed, S. (2016). Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia. Clinical ophthalmology (Auckland, NZ), 10, 1.
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697790/
dc.language.none.fl_str_mv en
dc.relation.none.fl_str_mv Clinical Ophthalmology
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.title.none.fl_str_mv Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
dc.type.none.fl_str_mv Article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description Purpose To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy. Patients and methods Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated. Results Twenty-two patients (35%) had RRD in the fellow eye, 37% of the eyes had cataract, 93% had macular detachment, 50% had proliferative vitreoretinopathy, and 41% had posterior vitreous detachment. Success rates were: 60% of patients after scleral buckling; 57.1% after pars plana vitrectomy; and 75% after combined scleral buckling and pars plana vitrectomy. Sixty-one (93.8%) of patients had successful surgery (including second surgery). Silicone oil tamponade was significantly associated with final anatomic outcome, with a protective odds ratio of 0.11 (P=0.027). Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P<0.001); preoperative cataract (P=0.023); and proliferative vitreoretinopathy (P<0.001). RRD developed in 16/44 eyes despite laser prophylaxis. Conclusion Prophylactic retinopexy was not beneficial for Stickler syndrome patients. Success of primary surgery for RRD remains low. The primary surgery should be vitrectomy combined with scleral buckling and silicone oil tamponade
eu_rights_str_mv openAccess
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id LAURepo_64265c5ed027fdd683d5ea22ad6fd3e5
identifier_str_mv 1177-5483
Alshahrani, S. T., Ghazi, N. G., & Al-Rashaed, S. (2016). Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia. Clinical ophthalmology (Auckland, NZ), 10, 1.
language_invalid_str_mv en
network_acronym_str LAURepo
network_name_str Lebanese American University repository
oai_identifier_str oai:laur.lau.edu.lb:10725/10831
publishDate 2016
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spelling Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi ArabiaAlshahrani, Saeed T.Ghazi, Nicola G.Al-Rashaed, SabaPurpose To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy. Patients and methods Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated. Results Twenty-two patients (35%) had RRD in the fellow eye, 37% of the eyes had cataract, 93% had macular detachment, 50% had proliferative vitreoretinopathy, and 41% had posterior vitreous detachment. Success rates were: 60% of patients after scleral buckling; 57.1% after pars plana vitrectomy; and 75% after combined scleral buckling and pars plana vitrectomy. Sixty-one (93.8%) of patients had successful surgery (including second surgery). Silicone oil tamponade was significantly associated with final anatomic outcome, with a protective odds ratio of 0.11 (P=0.027). Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P<0.001); preoperative cataract (P=0.023); and proliferative vitreoretinopathy (P<0.001). RRD developed in 16/44 eyes despite laser prophylaxis. Conclusion Prophylactic retinopexy was not beneficial for Stickler syndrome patients. Success of primary surgery for RRD remains low. The primary surgery should be vitrectomy combined with scleral buckling and silicone oil tamponadePublishedN/A2019-06-14T11:36:23Z2019-06-14T11:36:23Z20162019-06-14Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1177-5483http://hdl.handle.net/10725/10831https://doi.org/10.2147/OPTH.S91444Alshahrani, S. T., Ghazi, N. G., & Al-Rashaed, S. (2016). Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia. Clinical ophthalmology (Auckland, NZ), 10, 1.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697790/enClinical Ophthalmologyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/108312021-03-19T10:45:19Z
spellingShingle Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
Alshahrani, Saeed T.
status_str publishedVersion
title Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_full Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_fullStr Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_full_unstemmed Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_short Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_sort Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
url http://hdl.handle.net/10725/10831
https://doi.org/10.2147/OPTH.S91444
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697790/