Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts
The function of osteoclasts (OCs), multinucleated giant cells (MGCs) of the monocytic lineage, is bone resorption. To resorb bone, OCs form podosomes. These are actin-rich adhesive structures that pattern into rings that drive OC migration and into “sealing-zones” (SZs) that confine the resorption l...
محفوظ في:
| المؤلف الرئيسي: | Georgess, Dan (author) |
|---|---|
| مؤلفون آخرون: | Mazzorana, Marlene (author), Terrado, Jose (author), Delpart, Chrisitne (author), Chamot, Christophe (author), Guasch, Rosa M. (author), Perez-Roger, Ignocia (author), Jurdic, Pierre (author), Machuca-Gayet, Irma (author) |
| التنسيق: | article |
| منشور في: |
2014
|
| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/10338 https://doi.org/10.1091/mbc.e13-07-0363 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.molbiolcell.org/doi/full/10.1091/mbc.e13-07-0363 |
| الوسوم: |
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