Cognition and physical functioning in patients with schizophrenia: any role for vitamin D?
Aim: The study’s objective was to evaluate the relationship between vitamin D (VD) levels and cognitive performance in patients with schizophrenia. Methods: A cross-sectional study, conducted between March and July 2016, recruited 196 patients with schizophrenia. The Brief Cognitive Rating Scale (BC...
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2019
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| Online Access: | http://hdl.handle.net/10725/10307 https://doi.org/10.1080/1028415X.2019.1580830 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.tandfonline.com/doi/abs/10.1080/1028415X.2019.1580830 |
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| _version_ | 1864513486246117376 |
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| author | Azar, Jocelyne |
| author2 | Zoghbi, Marouan Haddad, Chadi Hallit, Souheil Nabout, Rita Medlej-Hashim, Myrna Hachem, Dory |
| author2_role | author author author author author author |
| author_facet | Azar, Jocelyne Zoghbi, Marouan Haddad, Chadi Hallit, Souheil Nabout, Rita Medlej-Hashim, Myrna Hachem, Dory |
| author_role | author |
| dc.creator.none.fl_str_mv | Azar, Jocelyne Zoghbi, Marouan Haddad, Chadi Hallit, Souheil Nabout, Rita Medlej-Hashim, Myrna Hachem, Dory |
| dc.date.none.fl_str_mv | 2019-04-01T08:38:57Z 2019-04-01T08:38:57Z 2019 2019-04-01 |
| dc.identifier.none.fl_str_mv | 1476-8305 http://hdl.handle.net/10725/10307 https://doi.org/10.1080/1028415X.2019.1580830 Zoghbi, M., Haddad, C., Hallit, S., Nabout, R., Medlej-Hashim, M., Hachem, D., & Azar, J. (2019). Cognition and physical functioning in patients with schizophrenia: any role for vitamin D?. Nutritional neuroscience, 1-9. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.tandfonline.com/doi/abs/10.1080/1028415X.2019.1580830 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Nutritional Neuroscience |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Aim: The study’s objective was to evaluate the relationship between vitamin D (VD) levels and cognitive performance in patients with schizophrenia. Methods: A cross-sectional study, conducted between March and July 2016, recruited 196 patients with schizophrenia. The Brief Cognitive Rating Scale (BCRS) and the Morningside Rehabilitation Status Scale (MRSS) were used to measure the severity of cognitive impairment and the level of general functioning in psychiatric patients. Lower scores for both scales indicate a better cognition and functioning respectively. Vitamin D levels of participants were divided into four groups: severe VD deficiency (<10 ng/ml), VD deficiency (10–20 ng/ml), VD insufficiency (20–30 ng/ml), VD sufficiency (>30 ng/ml). Relationships between VD level and cognition and functioning were assessed by analyses of covariance and hierarchical multiple regression, adjusted for age, gender, marital status, education level, sun exposure, physical activity and monthly income. Results: Severe VD deficiency was found in 22 patients with schizophrenia (11.3%), while 45.6% of patients had VD deficiency. Severe VD deficiency was significantly associated with an increase in MRSS score after adjusting for covariates (Beta = 2.44), however, no significant association was found with the BCRS score. Conclusion: These findings suggest that severe VD deficiency in patients with schizophrenia might be associated with low general functioning but could not influence cognitive function. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_6cc81ca1bf3620b1ebdd1441d6e8b0d4 |
| identifier_str_mv | 1476-8305 Zoghbi, M., Haddad, C., Hallit, S., Nabout, R., Medlej-Hashim, M., Hachem, D., & Azar, J. (2019). Cognition and physical functioning in patients with schizophrenia: any role for vitamin D?. Nutritional neuroscience, 1-9. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/10307 |
| publishDate | 2019 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D?Azar, JocelyneZoghbi, MarouanHaddad, ChadiHallit, SouheilNabout, RitaMedlej-Hashim, MyrnaHachem, DoryAim: The study’s objective was to evaluate the relationship between vitamin D (VD) levels and cognitive performance in patients with schizophrenia. Methods: A cross-sectional study, conducted between March and July 2016, recruited 196 patients with schizophrenia. The Brief Cognitive Rating Scale (BCRS) and the Morningside Rehabilitation Status Scale (MRSS) were used to measure the severity of cognitive impairment and the level of general functioning in psychiatric patients. Lower scores for both scales indicate a better cognition and functioning respectively. Vitamin D levels of participants were divided into four groups: severe VD deficiency (<10 ng/ml), VD deficiency (10–20 ng/ml), VD insufficiency (20–30 ng/ml), VD sufficiency (>30 ng/ml). Relationships between VD level and cognition and functioning were assessed by analyses of covariance and hierarchical multiple regression, adjusted for age, gender, marital status, education level, sun exposure, physical activity and monthly income. Results: Severe VD deficiency was found in 22 patients with schizophrenia (11.3%), while 45.6% of patients had VD deficiency. Severe VD deficiency was significantly associated with an increase in MRSS score after adjusting for covariates (Beta = 2.44), however, no significant association was found with the BCRS score. Conclusion: These findings suggest that severe VD deficiency in patients with schizophrenia might be associated with low general functioning but could not influence cognitive function.PublishedN/A2019-04-01T08:38:57Z2019-04-01T08:38:57Z20192019-04-01Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1476-8305http://hdl.handle.net/10725/10307https://doi.org/10.1080/1028415X.2019.1580830Zoghbi, M., Haddad, C., Hallit, S., Nabout, R., Medlej-Hashim, M., Hachem, D., & Azar, J. (2019). Cognition and physical functioning in patients with schizophrenia: any role for vitamin D?. Nutritional neuroscience, 1-9.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.tandfonline.com/doi/abs/10.1080/1028415X.2019.1580830enNutritional Neuroscienceinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/103072021-03-19T10:45:25Z |
| spellingShingle | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? Azar, Jocelyne |
| status_str | publishedVersion |
| title | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| title_full | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| title_fullStr | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| title_full_unstemmed | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| title_short | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| title_sort | Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? |
| url | http://hdl.handle.net/10725/10307 https://doi.org/10.1080/1028415X.2019.1580830 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.tandfonline.com/doi/abs/10.1080/1028415X.2019.1580830 |