Interactions between riluzole and ABCG2/BCRP transporter

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disease. Drugs used in this disease need to cross the blood–brain barrier (BBB). Only riluzole is approved for ALS treatment. We have investigated riluzole as a breast cancer resistance protein (BCRP) substrate by studying its brain tr...

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Bibliographic Details
Main Author: Milane, Aline (author)
Other Authors: Vautier, Sarah (author), Chacun, Helene (author), Meininger, Vincent (author), Bensimon, Gilbert (author), Farinotti, Robert (author), Fernandez, Christine (author)
Format: article
Published: 2009
Online Access:http://hdl.handle.net/10725/4498
http://dx.doi.org/10.1016/j.neulet.2008.12.061
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.sciencedirect.com/science/article/pii/S0304394009000020
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