Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa
Background Very few studies have investigated the relationship between malnutrition and psychological symptoms in Anorexia Nervosa (AN). They have used only body weight or body mass index (BMI) for the nutritional assessment and did not always report on medication, or if they did, it was not include...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| التنسيق: | article |
| منشور في: |
2013
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/6210 https://doi.org/10.1371/annotation/2590ee07-f8c4-42c7-8ccd-f3b8ca79c59c http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049380 |
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إضافة وسم
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| _version_ | 1864513478913425408 |
|---|---|
| author | Mattar, L. |
| author2 | Huas, C. Godart, N. |
| author2_role | author author |
| author_facet | Mattar, L. Huas, C. Godart, N. |
| author_role | author |
| dc.creator.none.fl_str_mv | Mattar, L. Huas, C. Godart, N. |
| dc.date.none.fl_str_mv | 2013 2017-09-15T13:08:24Z 2017-09-15T13:08:24Z 2017-09-15 |
| dc.identifier.none.fl_str_mv | 1932-6203 http://hdl.handle.net/10725/6210 https://doi.org/10.1371/annotation/2590ee07-f8c4-42c7-8ccd-f3b8ca79c59c Mattar, L., Huas, C., & Godart, N. (2012). Relationship between affective symptoms and malnutrition severity in severe Anorexia Nervosa. PloS one, 7(11), e49380. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049380 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Plos one |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Background Very few studies have investigated the relationship between malnutrition and psychological symptoms in Anorexia Nervosa (AN). They have used only body weight or body mass index (BMI) for the nutritional assessment and did not always report on medication, or if they did, it was not included in the analysis of results, and they did not include confounding factors such as duration of illness, AN subtype or age. The present study investigates this relationship using indicators other than BMI/weight, among which body composition and biological markers, also considering potential confounders related to depression and anxiety. Methods 155 AN patients, (DSM-IV) were included consecutively upon admission to inpatient treatment. Depression, anxiety, obsessive behaviours and social functioning were measured using various scales. Nutritional status was measured using BMI, severity of weight loss, body composition, and albumin and prealbumin levels. Results No correlation was found between BMI at inclusion, fat-free mass index, fat mass index, and severity of weight loss and any of the psychometric scores. Age and medication are the only factors that affect the psychological scores. None of the psychological scores were explained by the nutritional indicators with the exception of albumin levels which was negatively linked to the LSAS fear score (p = 0.024; beta = −0.225). Only the use of antidepressants explained the variability in BDI scores (p = 0.029; beta = 0.228) and anxiolytic use explained the variability in HADs depression scores (p = 0.037; beta = 0.216). Conclusion The present study is a pioneer investigation of various nutritional markers in relation to psychological symptoms in severely malnourished AN patients. The clinical hypothesis that malnutrition partly causes depression and anxiety symptoms in AN in acute phase is not confirmed, and future studies are needed to back up our results. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_789727f5d2414c191a61d6deebf35446 |
| identifier_str_mv | 1932-6203 Mattar, L., Huas, C., & Godart, N. (2012). Relationship between affective symptoms and malnutrition severity in severe Anorexia Nervosa. PloS one, 7(11), e49380. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/6210 |
| publishDate | 2013 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosaMattar, L.Huas, C.Godart, N.Background Very few studies have investigated the relationship between malnutrition and psychological symptoms in Anorexia Nervosa (AN). They have used only body weight or body mass index (BMI) for the nutritional assessment and did not always report on medication, or if they did, it was not included in the analysis of results, and they did not include confounding factors such as duration of illness, AN subtype or age. The present study investigates this relationship using indicators other than BMI/weight, among which body composition and biological markers, also considering potential confounders related to depression and anxiety. Methods 155 AN patients, (DSM-IV) were included consecutively upon admission to inpatient treatment. Depression, anxiety, obsessive behaviours and social functioning were measured using various scales. Nutritional status was measured using BMI, severity of weight loss, body composition, and albumin and prealbumin levels. Results No correlation was found between BMI at inclusion, fat-free mass index, fat mass index, and severity of weight loss and any of the psychometric scores. Age and medication are the only factors that affect the psychological scores. None of the psychological scores were explained by the nutritional indicators with the exception of albumin levels which was negatively linked to the LSAS fear score (p = 0.024; beta = −0.225). Only the use of antidepressants explained the variability in BDI scores (p = 0.029; beta = 0.228) and anxiolytic use explained the variability in HADs depression scores (p = 0.037; beta = 0.216). Conclusion The present study is a pioneer investigation of various nutritional markers in relation to psychological symptoms in severely malnourished AN patients. The clinical hypothesis that malnutrition partly causes depression and anxiety symptoms in AN in acute phase is not confirmed, and future studies are needed to back up our results.PublishedN/A2017-09-15T13:08:24Z2017-09-15T13:08:24Z20132017-09-15Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1932-6203http://hdl.handle.net/10725/6210https://doi.org/10.1371/annotation/2590ee07-f8c4-42c7-8ccd-f3b8ca79c59cMattar, L., Huas, C., & Godart, N. (2012). Relationship between affective symptoms and malnutrition severity in severe Anorexia Nervosa. PloS one, 7(11), e49380.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049380enPlos oneinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/62102021-03-19T10:43:10Z |
| spellingShingle | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa Mattar, L. |
| status_str | publishedVersion |
| title | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| title_full | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| title_fullStr | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| title_full_unstemmed | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| title_short | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| title_sort | Relationship between affectives symptoms and malnutrition severity in severe anorexia nervosa |
| url | http://hdl.handle.net/10725/6210 https://doi.org/10.1371/annotation/2590ee07-f8c4-42c7-8ccd-f3b8ca79c59c http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049380 |