Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults

Objective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. Pharmacological treatments have been previously critiqued, so researchers are focu...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Ezzeddine, Maha (author)
التنسيق: masterThesis
منشور في: 2021
الموضوعات:
الوصول للمادة أونلاين:http://hdl.handle.net/10725/13673
https://doi.org/10.26756/th.2022.239
http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php
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author Ezzeddine, Maha
author_facet Ezzeddine, Maha
author_role author
dc.creator.none.fl_str_mv Ezzeddine, Maha
dc.date.none.fl_str_mv 2021
2021-07-02
2022-06-15T07:59:26Z
2022-06-15T07:59:26Z
dc.identifier.none.fl_str_mv http://hdl.handle.net/10725/13673
https://doi.org/10.26756/th.2022.239
http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php
dc.language.none.fl_str_mv en
dc.publisher.none.fl_str_mv Lebanese American University
dc.rights.*.fl_str_mv info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cognition in old age -- Lebanon -- Evaluation
Cognition -- Age factors
Older people -- Health and hygiene -- Lebanon
Lebanese American University -- Dissertations
Dissertations, Academic
dc.title.none.fl_str_mv Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
dc.type.none.fl_str_mv Thesis
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/masterThesis
description Objective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. Pharmacological treatments have been previously critiqued, so researchers are focusing now on studying the nonpharmacological strategies against cognitive decline. Adopting a healthy lifestyle that constitute of following a healthy diet, consuming moderate alcohol amount, being physically active, maintaining a healthy BMI and never smoking is an important protective factor against cognitive decline. Since Lebanon ranks the highest percentage of dementia among the Arab countries and studies assessing this effect are still scarce, the aim of this study was to establish the association between a healthy lifestyle and cognitive decline. Methods: This is a secondary cross-sectional data analysis conducted on 502 community dwelling Lebanese older adults aged ≥ 65 years old and their informants recruited from two main governorates in Lebanon: Beirut and Mount Lebanon. Cognitive decline was assessed using three measurement tools: RUDAS, IQCODE and 10/66 DRG and the healthy lifestyle index (HLI) was based on 5 components: diet, BMI, alcohol, physical activity and smoking with a score ranging from 0 to 20. Three categories were created based on statistical quartiles and lowest (Q1), intermediate (Q2-Q3) and highest adherence to HLI were compared. Logistic regressions were performed to assess the relationship between HLI and prevalence of cognitive decline while adjusting for: age, gender, marital status, education, number of chronic diseases, medications, depression, and social activity. Results: The final sample size included 432 participants with an average age of 72.4 years and constituted of 56.7% females. One third were cognitively declined and they were more likely to be females (p=0.002), older in age (p=0.002), had lower levels of education (p=0.008), took more medications (p=0.027), were less socially active (p=0.02) and in general they followed a less healthy lifestyle. Participants in the highest HLI category had a significantly lower prevalence of cognitive decline as demonstrated by RUDAS (p<0.0001) and IQCODE (p<0.0001), but not by 10/66DRG (p=0.069). Lastly, participants with the highest adherence to HLI had a 77% lower prevalence of cognitive decline when assessed by RUDAS (OR: 0.23, 95%CI: 0.12-0.45, p<0.0001), but this association was not significant when assessed by IQCODE and 10/66 DRG. Conclusion: The results showed that a healthy lifestyle might contribute to a lower prevalence of cognitive decline in older adults. Longitudinal prospective studies should be performed to assess the effect of adherence to a healthy lifestyle on cognition at early and late-life stages.
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spelling Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older AdultsEzzeddine, MahaCognition in old age -- Lebanon -- EvaluationCognition -- Age factorsOlder people -- Health and hygiene -- LebanonLebanese American University -- DissertationsDissertations, AcademicObjective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. Pharmacological treatments have been previously critiqued, so researchers are focusing now on studying the nonpharmacological strategies against cognitive decline. Adopting a healthy lifestyle that constitute of following a healthy diet, consuming moderate alcohol amount, being physically active, maintaining a healthy BMI and never smoking is an important protective factor against cognitive decline. Since Lebanon ranks the highest percentage of dementia among the Arab countries and studies assessing this effect are still scarce, the aim of this study was to establish the association between a healthy lifestyle and cognitive decline. Methods: This is a secondary cross-sectional data analysis conducted on 502 community dwelling Lebanese older adults aged ≥ 65 years old and their informants recruited from two main governorates in Lebanon: Beirut and Mount Lebanon. Cognitive decline was assessed using three measurement tools: RUDAS, IQCODE and 10/66 DRG and the healthy lifestyle index (HLI) was based on 5 components: diet, BMI, alcohol, physical activity and smoking with a score ranging from 0 to 20. Three categories were created based on statistical quartiles and lowest (Q1), intermediate (Q2-Q3) and highest adherence to HLI were compared. Logistic regressions were performed to assess the relationship between HLI and prevalence of cognitive decline while adjusting for: age, gender, marital status, education, number of chronic diseases, medications, depression, and social activity. Results: The final sample size included 432 participants with an average age of 72.4 years and constituted of 56.7% females. One third were cognitively declined and they were more likely to be females (p=0.002), older in age (p=0.002), had lower levels of education (p=0.008), took more medications (p=0.027), were less socially active (p=0.02) and in general they followed a less healthy lifestyle. Participants in the highest HLI category had a significantly lower prevalence of cognitive decline as demonstrated by RUDAS (p<0.0001) and IQCODE (p<0.0001), but not by 10/66DRG (p=0.069). Lastly, participants with the highest adherence to HLI had a 77% lower prevalence of cognitive decline when assessed by RUDAS (OR: 0.23, 95%CI: 0.12-0.45, p<0.0001), but this association was not significant when assessed by IQCODE and 10/66 DRG. Conclusion: The results showed that a healthy lifestyle might contribute to a lower prevalence of cognitive decline in older adults. Longitudinal prospective studies should be performed to assess the effect of adherence to a healthy lifestyle on cognition at early and late-life stages.1 online resource (xii, 106 leaves): col. ill.Includes bibliographical references (leaf 75-103)Lebanese American University2022-06-15T07:59:26Z2022-06-15T07:59:26Z20212021-07-02Thesisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesishttp://hdl.handle.net/10725/13673https://doi.org/10.26756/th.2022.239http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.phpeninfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/136732022-07-05T09:10:22Z
spellingShingle Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
Ezzeddine, Maha
Cognition in old age -- Lebanon -- Evaluation
Cognition -- Age factors
Older people -- Health and hygiene -- Lebanon
Lebanese American University -- Dissertations
Dissertations, Academic
status_str publishedVersion
title Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
title_full Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
title_fullStr Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
title_full_unstemmed Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
title_short Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
title_sort Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults
topic Cognition in old age -- Lebanon -- Evaluation
Cognition -- Age factors
Older people -- Health and hygiene -- Lebanon
Lebanese American University -- Dissertations
Dissertations, Academic
url http://hdl.handle.net/10725/13673
https://doi.org/10.26756/th.2022.239
http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php