Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation

Apoptosis is implicated in the fragmentation of preimplantation mammalian embryos, yet the extent of this association remains controversial. The aim of this study was to assess the ability of sphingosine-1-phosphate (S1P), a known anti-apoptotic substance, to reduce the fragmentation rate of human p...

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Bibliographic Details
Main Author: Zreik, Tony (author)
Other Authors: Hannoun, Antoine (author), Abu-Musa, Antoine (author), Hajameh, Fatiha (author), Awwad, Johnny (author)
Format: article
Published: 2010
Online Access:http://hdl.handle.net/10725/2298
http://dx.doi.org/10.1016/j.rbmo.2009.11.020
http://www.sciencedirect.com/science/article/pii/S1472648309002715
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