Metastatic parotid myoepithelial carcinoma in a 7-year-old boy
Myoepithelial carcinoma is a rare malignancy of the parotid gland that is usually seen in adults. We report the first case in children of myoepithelial carcinoma of the parotid gland with massive invasion of the facial nerve and metastasis to cervical lymph nodes. Due to its rarity, the treatment an...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , |
| التنسيق: | article |
| منشور في: |
2012
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/5172 http://dx.doi.org/10.1155/2012/212746 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.hindawi.com/journals/cripe/2012/212746/abs/ |
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| _version_ | 1864513465349046272 |
|---|---|
| author | Nasser, Selim |
| author2 | Saliba, Issam El Khatib, Nazir Nahme, Antoine Moukarzel, Nabil |
| author2_role | author author author author |
| author_facet | Nasser, Selim Saliba, Issam El Khatib, Nazir Nahme, Antoine Moukarzel, Nabil |
| author_role | author |
| dc.creator.none.fl_str_mv | Nasser, Selim Saliba, Issam El Khatib, Nazir Nahme, Antoine Moukarzel, Nabil |
| dc.date.none.fl_str_mv | 2012 2017-02-03T11:37:27Z 2017-02-03T11:37:27Z 2017-02-03 |
| dc.identifier.none.fl_str_mv | 2090-6803 http://hdl.handle.net/10725/5172 http://dx.doi.org/10.1155/2012/212746 Saliba, I., El Khatib, N., Nehme, A., Nasser, S., & Moukarzel, N. (2012). Metastatic parotid myoepithelial carcinoma in a 7-year-old boy. Case reports in pediatrics, 2012. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.hindawi.com/journals/cripe/2012/212746/abs/ |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Case Reports in Pediatrics |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Myoepithelial carcinoma is a rare malignancy of the parotid gland that is usually seen in adults. We report the first case in children of myoepithelial carcinoma of the parotid gland with massive invasion of the facial nerve and metastasis to cervical lymph nodes. Due to its rarity, the treatment and the clinical course of this tumor are not well defined yet. We performed a total parotidectomy, a modified neck dissection, and a postoperative radiotherapy in 7-year-old boy. Sparing of the facial nerve was impossible; it was sacrificed and grafted with a sural nerve. Histopathology confirmed the diagnosis of a parotid gland carcinoma and immunohistochemical markers showed that the tumor cells express cytokeratin, epithelial membrane antigen, cytokeratin 7, smooth muscle actin, P63, CEA, and S100. This pattern of immunostaining is consistent with the diagnosis of myoepithelial carcinoma. On the postoperative tenth month he presented with a pulmonary and lumbar vertebra metastasis. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_875dbd0be60e3df54d2e57a8897a0f33 |
| identifier_str_mv | 2090-6803 Saliba, I., El Khatib, N., Nehme, A., Nasser, S., & Moukarzel, N. (2012). Metastatic parotid myoepithelial carcinoma in a 7-year-old boy. Case reports in pediatrics, 2012. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/5172 |
| publishDate | 2012 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Metastatic parotid myoepithelial carcinoma in a 7-year-old boyNasser, SelimSaliba, IssamEl Khatib, NazirNahme, AntoineMoukarzel, NabilMyoepithelial carcinoma is a rare malignancy of the parotid gland that is usually seen in adults. We report the first case in children of myoepithelial carcinoma of the parotid gland with massive invasion of the facial nerve and metastasis to cervical lymph nodes. Due to its rarity, the treatment and the clinical course of this tumor are not well defined yet. We performed a total parotidectomy, a modified neck dissection, and a postoperative radiotherapy in 7-year-old boy. Sparing of the facial nerve was impossible; it was sacrificed and grafted with a sural nerve. Histopathology confirmed the diagnosis of a parotid gland carcinoma and immunohistochemical markers showed that the tumor cells express cytokeratin, epithelial membrane antigen, cytokeratin 7, smooth muscle actin, P63, CEA, and S100. This pattern of immunostaining is consistent with the diagnosis of myoepithelial carcinoma. On the postoperative tenth month he presented with a pulmonary and lumbar vertebra metastasis.PublishedN/A2017-02-03T11:37:27Z2017-02-03T11:37:27Z20122017-02-03Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2090-6803http://hdl.handle.net/10725/5172http://dx.doi.org/10.1155/2012/212746Saliba, I., El Khatib, N., Nehme, A., Nasser, S., & Moukarzel, N. (2012). Metastatic parotid myoepithelial carcinoma in a 7-year-old boy. Case reports in pediatrics, 2012.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttps://www.hindawi.com/journals/cripe/2012/212746/abs/enCase Reports in Pediatricsinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/51722021-03-19T10:00:53Z |
| spellingShingle | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy Nasser, Selim |
| status_str | publishedVersion |
| title | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| title_full | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| title_fullStr | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| title_full_unstemmed | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| title_short | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| title_sort | Metastatic parotid myoepithelial carcinoma in a 7-year-old boy |
| url | http://hdl.handle.net/10725/5172 http://dx.doi.org/10.1155/2012/212746 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.hindawi.com/journals/cripe/2012/212746/abs/ |