Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon
Escherichia coli is the most common causative agent of recurrent, uncomplicated urinary tract infections. Triplex PCR and the disc diffusion method were used to determine and correlate among the phylogenetic group, virulence determinants and antimicrobial resistance in 100 uropathogens. Group B2 rep...
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2013
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| Online Access: | http://hdl.handle.net/10725/5102 http://dx.doi.org/10.1179/joc.2009.21.2.153 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.tandfonline.com/doi/abs/10.1179/joc.2009.21.2.153 |
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| _version_ | 1864513465032376320 |
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| author | Hashwa, F. |
| author2 | Tokajian, S. Sawma-Aouad, G. |
| author2_role | author author |
| author_facet | Hashwa, F. Tokajian, S. Sawma-Aouad, G. |
| author_role | author |
| dc.creator.none.fl_str_mv | Hashwa, F. Tokajian, S. Sawma-Aouad, G. |
| dc.date.none.fl_str_mv | 2013 2017-01-30T09:17:50Z 2017-01-30T09:17:50Z 2017-01-30 |
| dc.identifier.none.fl_str_mv | 1120-009X http://hdl.handle.net/10725/5102 http://dx.doi.org/10.1179/joc.2009.21.2.153 Sawma-Aouad, G., Hashwa, F., & Tokajian, S. (2009). Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic Escherichia coli in Lebanon. Journal of Chemotherapy, 21(2), 153-158. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.tandfonline.com/doi/abs/10.1179/joc.2009.21.2.153 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | Journal of Chemotherapy |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Escherichia coli is the most common causative agent of recurrent, uncomplicated urinary tract infections. Triplex PCR and the disc diffusion method were used to determine and correlate among the phylogenetic group, virulence determinants and antimicrobial resistance in 100 uropathogens. Group B2 represented 58% of the tested isolates with no isolates belonging to group B1. Isolates with the highest percentage of susceptibility to all antimicrobial agents used were within the B2 phylogenetic groups. 38% of the tested population were resistant to trimethoprim/sulfamethoxazole, 29% to ciprofloxacin and only 8% to nitrofurantoin. The majority of the isolates resistant to trimethoprim/sulfamethoxazole were from group B2 (52.7%), with 45% being positive to the three tested virulence determinants (efu, fbp and picU). These findings suggest that although virulence and antimicrobial resistance are mutually exclusive in Escherichia coli clinical isolates, the relationship between virulence and resistance to antimicrobial agents can vary according to the particular resistance phenotype. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_89f9bf365a46877c77b53a1f4c54dcfd |
| identifier_str_mv | 1120-009X Sawma-Aouad, G., Hashwa, F., & Tokajian, S. (2009). Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic Escherichia coli in Lebanon. Journal of Chemotherapy, 21(2), 153-158. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/5102 |
| publishDate | 2013 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in LebanonHashwa, F.Tokajian, S.Sawma-Aouad, G.Escherichia coli is the most common causative agent of recurrent, uncomplicated urinary tract infections. Triplex PCR and the disc diffusion method were used to determine and correlate among the phylogenetic group, virulence determinants and antimicrobial resistance in 100 uropathogens. Group B2 represented 58% of the tested isolates with no isolates belonging to group B1. Isolates with the highest percentage of susceptibility to all antimicrobial agents used were within the B2 phylogenetic groups. 38% of the tested population were resistant to trimethoprim/sulfamethoxazole, 29% to ciprofloxacin and only 8% to nitrofurantoin. The majority of the isolates resistant to trimethoprim/sulfamethoxazole were from group B2 (52.7%), with 45% being positive to the three tested virulence determinants (efu, fbp and picU). These findings suggest that although virulence and antimicrobial resistance are mutually exclusive in Escherichia coli clinical isolates, the relationship between virulence and resistance to antimicrobial agents can vary according to the particular resistance phenotype.PublishedN/A2017-01-30T09:17:50Z2017-01-30T09:17:50Z20132017-01-30Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1120-009Xhttp://hdl.handle.net/10725/5102http://dx.doi.org/10.1179/joc.2009.21.2.153Sawma-Aouad, G., Hashwa, F., & Tokajian, S. (2009). Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic Escherichia coli in Lebanon. Journal of Chemotherapy, 21(2), 153-158.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://www.tandfonline.com/doi/abs/10.1179/joc.2009.21.2.153enJournal of Chemotherapyinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/51022021-03-19T10:03:22Z |
| spellingShingle | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon Hashwa, F. |
| status_str | publishedVersion |
| title | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| title_full | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| title_fullStr | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| title_full_unstemmed | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| title_short | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| title_sort | Antimicrobial resistance in relation to virulence determinants and phylogenetic background among uropathogenic escherichia coli in Lebanon |
| url | http://hdl.handle.net/10725/5102 http://dx.doi.org/10.1179/joc.2009.21.2.153 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.tandfonline.com/doi/abs/10.1179/joc.2009.21.2.153 |