Penicillin-resistant streptococcus pneumoniae in Lebanon
A total of 123 clinical isolates of Streptococcus pneumoniae were collected from all over Lebanon and tested for their susceptibility to penicillin: 30.1% were susceptible (minimum inhibitory concentration (MIC) ≤ 0.06 μg/mL), 56.1% were intermediately susceptible (MIC 0.09–1.0 μg/mL) and 13.8% were...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , |
| التنسيق: | article |
| منشور في: |
2006
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/5205 http://dx.doi.org/10.1016/j.ijantimicag.2005.10.019 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.sciencedirect.com/science/article/pii/S0924857905003547 |
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| _version_ | 1864513465386795008 |
|---|---|
| author | Mokhbat, Jacques E. |
| author2 | Uwaydah, Marwan Karam-Sarkis, Dolla Baroud-Nassif, Rita Rohban, Thomas |
| author2_role | author author author author |
| author_facet | Mokhbat, Jacques E. Uwaydah, Marwan Karam-Sarkis, Dolla Baroud-Nassif, Rita Rohban, Thomas |
| author_role | author |
| dc.creator.none.fl_str_mv | Mokhbat, Jacques E. Uwaydah, Marwan Karam-Sarkis, Dolla Baroud-Nassif, Rita Rohban, Thomas |
| dc.date.none.fl_str_mv | 2006 2017-02-10T08:44:06Z 2017-02-10T08:44:06Z 2017-02-10 |
| dc.identifier.none.fl_str_mv | 0924-8579 http://hdl.handle.net/10725/5205 http://dx.doi.org/10.1016/j.ijantimicag.2005.10.019 Uwaydah, M., Mokhbat, J. E., Karam-Sarkis, D., Baroud-Nassif, R., & Rohban, T. (2006). Penicillin-resistant Streptococcus pneumoniae in Lebanon: the first nationwide study. International journal of antimicrobial agents, 27(3), 242-246. http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.sciencedirect.com/science/article/pii/S0924857905003547 |
| dc.language.none.fl_str_mv | en |
| dc.relation.none.fl_str_mv | International Journal of Antimicrobial Agents |
| dc.rights.*.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.title.none.fl_str_mv | Penicillin-resistant streptococcus pneumoniae in Lebanon the first nationwide study |
| dc.type.none.fl_str_mv | Article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | A total of 123 clinical isolates of Streptococcus pneumoniae were collected from all over Lebanon and tested for their susceptibility to penicillin: 30.1% were susceptible (minimum inhibitory concentration (MIC) ≤ 0.06 μg/mL), 56.1% were intermediately susceptible (MIC 0.09–1.0 μg/mL) and 13.8% were resistant (MIC > 1.0 μg/mL). The oxacillin disk screening test detected all penicillin-resistant isolates, but erroneously designated two penicillin-intermediate isolates as penicillin susceptible. All isolates were consistently susceptible to levofloxacin, but cross-resistance between penicillin and the three tested cephalosporins was frequently noted. The in vitro activity of amoxicillin/clavulanic acid paralleled that of penicillin; however, 92.7% of the isolates were designated as susceptible based on the recommended interpretive cut-off point (MIC ≤ 2/1 μg/mL). This discrepancy represents a paradox that deserves serious consideration. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | LAURepo_8d0cf63954ad24a4c4fca724e831af4e |
| identifier_str_mv | 0924-8579 Uwaydah, M., Mokhbat, J. E., Karam-Sarkis, D., Baroud-Nassif, R., & Rohban, T. (2006). Penicillin-resistant Streptococcus pneumoniae in Lebanon: the first nationwide study. International journal of antimicrobial agents, 27(3), 242-246. |
| language_invalid_str_mv | en |
| network_acronym_str | LAURepo |
| network_name_str | Lebanese American University repository |
| oai_identifier_str | oai:laur.lau.edu.lb:10725/5205 |
| publishDate | 2006 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Penicillin-resistant streptococcus pneumoniae in Lebanonthe first nationwide studyMokhbat, Jacques E.Uwaydah, MarwanKaram-Sarkis, DollaBaroud-Nassif, RitaRohban, ThomasA total of 123 clinical isolates of Streptococcus pneumoniae were collected from all over Lebanon and tested for their susceptibility to penicillin: 30.1% were susceptible (minimum inhibitory concentration (MIC) ≤ 0.06 μg/mL), 56.1% were intermediately susceptible (MIC 0.09–1.0 μg/mL) and 13.8% were resistant (MIC > 1.0 μg/mL). The oxacillin disk screening test detected all penicillin-resistant isolates, but erroneously designated two penicillin-intermediate isolates as penicillin susceptible. All isolates were consistently susceptible to levofloxacin, but cross-resistance between penicillin and the three tested cephalosporins was frequently noted. The in vitro activity of amoxicillin/clavulanic acid paralleled that of penicillin; however, 92.7% of the isolates were designated as susceptible based on the recommended interpretive cut-off point (MIC ≤ 2/1 μg/mL). This discrepancy represents a paradox that deserves serious consideration.PublishedN/A2017-02-10T08:44:06Z2017-02-10T08:44:06Z20062017-02-10Articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article0924-8579http://hdl.handle.net/10725/5205http://dx.doi.org/10.1016/j.ijantimicag.2005.10.019Uwaydah, M., Mokhbat, J. E., Karam-Sarkis, D., Baroud-Nassif, R., & Rohban, T. (2006). Penicillin-resistant Streptococcus pneumoniae in Lebanon: the first nationwide study. International journal of antimicrobial agents, 27(3), 242-246.http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.phphttp://www.sciencedirect.com/science/article/pii/S0924857905003547enInternational Journal of Antimicrobial Agentsinfo:eu-repo/semantics/openAccessoai:laur.lau.edu.lb:10725/52052021-03-19T10:00:48Z |
| spellingShingle | Penicillin-resistant streptococcus pneumoniae in Lebanon Mokhbat, Jacques E. |
| status_str | publishedVersion |
| title | Penicillin-resistant streptococcus pneumoniae in Lebanon |
| title_full | Penicillin-resistant streptococcus pneumoniae in Lebanon |
| title_fullStr | Penicillin-resistant streptococcus pneumoniae in Lebanon |
| title_full_unstemmed | Penicillin-resistant streptococcus pneumoniae in Lebanon |
| title_short | Penicillin-resistant streptococcus pneumoniae in Lebanon |
| title_sort | Penicillin-resistant streptococcus pneumoniae in Lebanon |
| url | http://hdl.handle.net/10725/5205 http://dx.doi.org/10.1016/j.ijantimicag.2005.10.019 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://www.sciencedirect.com/science/article/pii/S0924857905003547 |