mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation

Despite its central position in oncogenic intracellular signaling networks, the role of mTORC1 in epithelial development has not been studied extensively in vivo. Here, we have used the epidermis as a model system to elucidate the cellular effects and signaling feedback sequelae of mTORC1 loss of fu...

Full description

Saved in:
Bibliographic Details
Main Author: Georgess, Dan (author)
Other Authors: Asrani, Kaushal (author), Sood, Akshay (author), Torres, Alba (author), Phatak, Pornima (author), Kaur, Harmisar (author)
Format: article
Published: 2017
Online Access:http://hdl.handle.net/10725/10343
https://doi.org/10.1172/JCI92893
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.jci.org/articles/view/92893
Tags: Add Tag
No Tags, Be the first to tag this record!